{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T17:11:37Z","timestamp":1784913097914,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PM&amp;R"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Exercises have been used to improve outcomes after stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine the effects of planned, structured, and repetitive exercises of the paretic lower limb for improving stair climbing performance after stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>MEDLINE, EMBASE, Cochrane Library, Allied and Complementary Medicine Database, and Physiotherapy Evidence Database (PEDro).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Review Methods<\/jats:title>\n                    <jats:p>Only randomized clinical trials were included. Participants in the reviewed studies were adults at any time after stroke. The experimental intervention consisted of exercises for the paretic lower limb in comparison with no intervention\/placebo. Outcome data related to stair climbing performance were extracted from the eligible trials and combined in meta\u2010analysis. The quality of included trials was assessed by the PEDro scores. The quality of evidence was determined according to the Grading of Recommendations Assessment, Development, and Evaluation system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nine trials, involving 314 participants, were included. The examined interventions were strength training, task\u2010oriented training, or a combination of strength training with aerobic or task\u2010oriented training. A random\u2010effect meta\u2010analysis provided very low\u2010quality evidence that exercises improved stair climbing performance by standardized mean difference 0.4 (95% confidence interval [CI], 0\u20130.8). When only trials that reported the time to ascent\/descent stairs were pooled, exercise improved stair climbing performance by 3.4\u2009seconds (95% CI, 0.4\u20136.5). No trials examined the maintenance of benefits beyond the intervention period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This systematic review provided very\u2010low\u2010quality evidence that 6\u2009weeks of planned, structured, and repetitive exercises, performed during 50\u2009minutes, four times per week, improve stair climbing performance of moderately disabled individuals with chronic stroke.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pmrj.13373","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:09:27Z","timestamp":1747148967000},"page":"1215-1224","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Exercise improves stair climbing performance after stroke: A systematic review of randomized trials with meta\u2010analysis"],"prefix":"10.1002","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6792-0819","authenticated-orcid":false,"given":"Lucas Rodrigues","family":"Nascimento","sequence":"first","affiliation":[{"name":"Center of Health Sciences, Discipline of Physiotherapy Universidade Federal do Esp\u00edrito Santo  Vit\u00f3ria Brazil"},{"name":"NeuroGroup, Discipline of Physiotherapy Universidade Federal de Minas Gerais  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda Marcele","family":"de Souza Oliveira","sequence":"additional","affiliation":[{"name":"Center of Health Sciences, Discipline of Physiotherapy Universidade Federal do Esp\u00edrito Santo  Vit\u00f3ria Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grazyelle Maria Silva Pereira","family":"de Moraes","sequence":"additional","affiliation":[{"name":"Center of Health Sciences, Discipline of Physiotherapy Universidade Federal do Esp\u00edrito Santo  Vit\u00f3ria Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7351-9247","authenticated-orcid":false,"given":"Augusto","family":"Boening","sequence":"additional","affiliation":[{"name":"Center of Health Sciences, Discipline of Physiotherapy Universidade Federal do Esp\u00edrito Santo  Vit\u00f3ria Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9906-9555","authenticated-orcid":false,"given":"K\u00eania Kiefer Parreiras","family":"de Menezes","sequence":"additional","affiliation":[{"name":"NeuroGroup, Discipline of Physiotherapy Universidade Federal de Minas Gerais  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estephane Mendes","family":"de Souza","sequence":"additional","affiliation":[{"name":"Center of Health Science and Sports (CEFID), Discipline of Physiotherapy Universidade do Estado de Santa Catarina  Florian\u00f3polis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme Silva","family":"Nunes","sequence":"additional","affiliation":[{"name":"Center of Health Science and Sports (CEFID), Discipline of Physiotherapy Universidade do Estado de Santa Catarina  Florian\u00f3polis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5398-5876","authenticated-orcid":false,"given":"Stella Maris","family":"Michaelsen","sequence":"additional","affiliation":[{"name":"Center of Health Science and Sports (CEFID), Discipline of Physiotherapy Universidade do Estado de Santa Catarina  Florian\u00f3polis Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphys.2021.02.014"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjpt.2017.04.001"},{"key":"e_1_2_7_4_1","first-page":"811","article-title":"Watch your step! Who can recover stair climbing independence after stroke?","volume":"54","author":"Morone G","year":"2018","journal-title":"Eur J Phys Rehabil Med"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphys.2018.02.012"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1191\/0269215504cr699oa"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0b013e31802ee464"},{"key":"e_1_2_7_8_1","volume-title":"2022 Cochrane handbook for systematic reviews of interventions version 6.3 (updated February 2022)","author":"Higgins JP","year":"2019"},{"key":"e_1_2_7_9_1","unstructured":"GarberCE BlissmerB DeschenesMR et al.American College of Sports Medicine 2011 American College of Sports Medicine."},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/854328"},{"key":"e_1_2_7_11_1","volume-title":"Introduction to Meta\u2010Analysis","author":"Borenstein M","year":"2011"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269215511420306"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.07.015"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/jscd.2001.123775"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1589\/jpts.25.1177"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/1545968318765692"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000127785.73065.34"},{"key":"e_1_2_7_18_1","first-page":"16871","article-title":"Effects of the bilateral isokinetic strengthening training on functional parameters, gait, and the quality of life in patients with stroke","volume":"8","author":"\u015een SB","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2008.01707.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(99)90018-7"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.2340\/16501977-1887"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1589\/jpts.24.1307"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000022"},{"key":"e_1_2_7_24_1","volume-title":"Foundations of Clinical Research: Applications to Practice","author":"Portney LG","year":"2009"}],"container-title":["PM&amp;R"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pmrj.13373","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:54:23Z","timestamp":1761663263000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pmrj.13373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,13]]},"references-count":23,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/pmrj.13373"],"URL":"https:\/\/doi.org\/10.1002\/pmrj.13373","archive":["Portico"],"relation":{},"ISSN":["1934-1482","1934-1563"],"issn-type":[{"value":"1934-1482","type":"print"},{"value":"1934-1563","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,13]]},"assertion":[{"value":"2024-04-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}