{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T10:48:28Z","timestamp":1787827708243,"version":"build-2784847793"},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PM&R"],"published-print":{"date-parts":[[2026,5]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Quantitative muscle ultrasound (qMUS) provides morphological measurements that can support clinical observation of muscle atrophy and weakness. As the use of qMUS continues to expand, and its potential for broader implementation in neuromuscular evaluation grows, there is a clear need for further validation, particularly in pathologies frequently encountered in electrodiagnostic laboratories, such as cubital tunnel syndrome caused by ulnar neuropathy at the elbow (UNE).<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To evaluate the validity of qMUS evaluation of ulnar\u2010innervated intrinsic hand muscles.<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Cross\u2010sectional study.<\/jats:p>\n <\/jats:sec>\n \n Participants<\/jats:title>\n Individuals 18\u2009years or older with chronic UNE and healthy controls (HC).<\/jats:p>\n <\/jats:sec>\n \n Main Outcome Measurement<\/jats:title>\n qMUS parameters (muscle thickness [MT], cross\u2010sectional area [CSA], echogenicity) were measured in the first dorsal interosseous (FDI) and abductor digiti minimi (ADM) and were correlated to corresponding negative peak amplitude of the compound muscle action potential measured (CMAP) and key pinch grip strength.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Sixteen adults (8 HC, 8 UNE) participated in the study. Key pinch strength was significantly correlated with FDI MT (\n r<\/jats:italic>\n \u2009=\u20090.45,\n p<\/jats:italic>\n \u2009=\u2009.03 [95% CI, 0.05\u20130.73]) and echogenicity (rho\u2009=\u2009\u22120.60,\n p<\/jats:italic>\n \u2009=\u2009.002 [95% CI, \u22120.82 to \u22120.24]). FDI MT and echogenicity explained 20% and 36% of pinch strength variance, respectively. Echogenicity was significantly correlated with corresponding CMAP amplitudes (FDI: rho\u2009=\u2009\u22120.59,\n p<\/jats:italic>\n \u2009=\u2009.004 [95% CI, \u22120.81 to \u22120.21]; ADM: rho\u2009=\u2009\u22120.62,\n p<\/jats:italic>\n \u2009=\u2009.002 [95% CI, \u22120.83 to \u22120.26]). No statistically significant relationship was found between key pinch strength and FDI CSA (\n r<\/jats:italic>\n \u2009=\u20090.35\n p<\/jats:italic>\n \u2009=\u2009.104 [95% CI, \u22120.08\u20130.67]). Furthermore, FDI CMAP was not significantly associated with FDI MT (rho\u2009=\u20090.14,\n p<\/jats:italic>\n \u2009=\u2009.55 [95% CI, \u22120.32\u20130.54]) or FDI CSA (rho\u2009=\u20090.041,\n p<\/jats:italic>\n \u2009=\u2009.86 [95% CI, 0.04\u20130.47]).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n qMUS measures of echogenicity and MT (indicators of muscle fibrosis and size, respectively), correlated with key pinch strength and CMAP amplitudes in the FDI and ADM, in a heterogenous group including UNE and HC limbs. qMUS parameters may provide useful complementary markers and deeper insight into neuromuscular health in entrapment neuropathy.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/pmrj.70020","type":"journal-article","created":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T07:08:44Z","timestamp":1759302524000},"page":"520-525","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ultrasonographic evaluation of ulnar innervated muscles in ulnar neuropathy at the elbow"],"prefix":"10.1002","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5611-6906","authenticated-orcid":false,"given":"Emmanuel","family":"Ogalo","sequence":"first","affiliation":[{"name":"International Collaboration on Repair Discoveries (ICORD), University of British Columbia Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee","family":"Bauer","sequence":"additional","affiliation":[{"name":"Division of Physical Medicine and Rehabilitation, Department of Medicine University of British Columbia Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Doherty","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Department of Surgery University of British Columbia Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean G.","family":"Bristol","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Department of Surgery University of British Columbia Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristine M.","family":"Chapman","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department of Medicine University of British Columbia Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"BC Neuromuscular Disease Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Krauss","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Department of Surgery Dalhousie University Halifax Nova Scotia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Berger","sequence":"additional","affiliation":[{"name":"International Collaboration on Repair Discoveries (ICORD), University of British Columbia Vancouver British Columbia Canada"},{"name":"Division of Physical Medicine and Rehabilitation, Department of Medicine University of British Columbia Vancouver British Columbia 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