{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T11:10:19Z","timestamp":1778325019625,"version":"3.51.4"},"reference-count":42,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T00:00:00Z","timestamp":1778284800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T00:00:00Z","timestamp":1778284800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PM&R"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Hypovitaminosis D is associated with adverse health outcomes, including increased mortality in patients with cancer. Although vitamin D insufficiency (23%\u201372%) and deficiency (20%\u201371%) are common among patients admitted to inpatient rehabilitation, their prevalence and predictors in cancer\u2010specific inpatient rehabilitation populations remain uncharacterized.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To determine the prevalence of hypovitaminosis D in adults with cancer admitted to acute inpatient rehabilitation and to identify demographic, clinical, laboratory, and functional predictors.<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Retrospective observational cohort study.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n An inpatient rehabilitation service within a tertiary cancer hospital.<\/jats:p>\n <\/jats:sec>\n \n Patients<\/jats:title>\n Consecutive adults with a cancer diagnosis admitted for acute inpatient rehabilitation between December 1, 2023, and May 24, 2024.<\/jats:p>\n <\/jats:sec>\n \n Interventions<\/jats:title>\n Not applicable.<\/jats:p>\n <\/jats:sec>\n \n Main Outcome Measure(s)<\/jats:title>\n The primary outcome was the prevalence of hypovitaminosis D (25\u2010hydroxyvitamin D\u2009\u2264\u200929\u2009ng\/mL). Secondary outcomes included predictors of hypovitaminosis D and evaluation of the timing and frequency of vitamin D supplementation upon index hospital admission, upon admission to inpatient rehabilitation, and at 3 and 6\u2009months post discharge.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Of 126 patients, 78 (62%) had hypovitaminosis D. Significant predictors included relatively younger age (median 66.0 vs 71.5\u2009years; effect size, 5.5 with 95% confidence interval [CI], 1.60\u20139.40,\n p<\/jats:italic>\n \u2009=\u2009.006) and presence of neurogenic bladder or bowel (16.7% vs 2.4%; odds ratio, 0.12 with 95% CI, 0.003\u20130.924,\n p<\/jats:italic>\n \u2009=\u2009.019). At hospital admission, 29% (\n n<\/jats:italic>\n \u2009=\u200936) were receiving supplementation, and 40% (\n n<\/jats:italic>\n \u2009=\u200951) initiated supplementation during inpatient rehabilitation. At 3 and 6 months post discharge, 48% (\n n<\/jats:italic>\n \u2009=\u200961) and 39% (\n n<\/jats:italic>\n \u2009=\u200949), respectively, had records of continued supplementation. Vitamin D supplementation was generally well tolerated during inpatient rehabilitation, with only minor side effects that were managed in three patients.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Hypovitaminosis D was highly prevalent among adult patients with cancer undergoing inpatient rehabilitation. Identified predictors, including relatively younger age and neurogenic bladder or bowel, may help guide targeted screening.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/pmrj.70151","type":"journal-article","created":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T10:59:16Z","timestamp":1778324356000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hypovitaminosis D in acute inpatient cancer rehabilitation: Prevalence, predictors, and practical implications"],"prefix":"10.1002","author":[{"given":"Jegy M.","family":"Tennison","sequence":"first","affiliation":[{"name":"Section of Physical Medicine and Rehabilitation, Department of Palliative, Rehabilitation, and Integrative Medicine The University of Texas MD Anderson Cancer Center Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minxing","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Biostatistics The University of Texas MD Anderson Cancer Center Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Areeba","family":"Hafeez","sequence":"additional","affiliation":[{"name":"McGovern Medical School at UTHealth Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ananya","family":"Krishnan","sequence":"additional","affiliation":[{"name":"The University of Texas Medical Branch John Sealy School of Medicine Galveston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9513-5167","authenticated-orcid":false,"given":"Sefia","family":"Khan","sequence":"additional","affiliation":[{"name":"The University of Texas Medical Branch John Sealy School of Medicine Galveston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rony","family":"Dev","sequence":"additional","affiliation":[{"name":"Section of Palliative Medicine, Department of Palliative, Rehabilitation, and Integrative Medicine The University of Texas MD Anderson Cancer Center Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonal","family":"Admane","sequence":"additional","affiliation":[{"name":"Section of Palliative Medicine, Department of Palliative, Rehabilitation, and Integrative Medicine The University of Texas MD Anderson Cancer Center Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Bruera","sequence":"additional","affiliation":[{"name":"Section of Palliative Medicine, Department of Palliative, Rehabilitation, and Integrative Medicine The University of Texas MD Anderson Cancer Center Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,5,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-60327-303-9_1","volume-title":"Vitamin D: Physiology, Molecular Biology, 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