{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T21:59:42Z","timestamp":1785103182492,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:00:00Z","timestamp":1785024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:00:00Z","timestamp":1785024000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PM&R"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Musculoskeletal ultrasound is widely used to assess joint and bursal effusions, yet the impact of moderate\u2010distance running on fluid accumulation in asymptomatic individuals remains unclear. Previous studies have shown mixed results depending on exercise type and timing, highlighting a gap in understanding transient physiological responses to common physical activity such as running.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To determine whether a 5\u2010km run induces detectable changes in fluid presence within selected joints and bursae in healthy adults, as assessed with musculoskeletal ultrasound.<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Prospective observational trial.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n Institutional setting at a university hospital.<\/jats:p>\n <\/jats:sec>\n \n Participants<\/jats:title>\n Thirty healthy adults (17 female, 13 male; ages 20\u201347\u2009years) without musculoskeletal symptoms or recent injuries were recruited. All participants completed the study.<\/jats:p>\n <\/jats:sec>\n \n Interventions<\/jats:title>\n Not applicable.<\/jats:p>\n <\/jats:sec>\n \n Main outcome measure(s)<\/jats:title>\n Binary (yes\/no) presence of fluid in the tendon sheath of the long head of the biceps brachii, deep infrapatellar bursa, retrocalcaneal bursa, and talocrural joint were assessed bilaterally with ultrasound at baseline, immediately post run, and 24\u2009hours post run.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Significant increases in fluid were observed 24\u2009hours post\u2010run in the retrocalcaneal bursa (left:\n p<\/jats:italic>\n \u2009<\u2009.001,\n g<\/jats:italic>\n \u2009=\u20090.46; right:\n p<\/jats:italic>\n \u2009<\u2009.001,\n g<\/jats:italic>\n \u2009=\u20090.40) and talocrural joint (left:\n p<\/jats:italic>\n \u2009=\u2009.001,\n g<\/jats:italic>\n \u2009=\u20090.36; right:\n p<\/jats:italic>\n \u2009=\u2009.002,\n g<\/jats:italic>\n \u2009=\u20090.33). long head of the biceps brachii showed transient changes (left:\n p<\/jats:italic>\n \u2009=\u2009.002 next day). No significant changes were found in the deep infrapatellar bursa (all\n p<\/jats:italic>\n \u2009>\u2009.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n A short 5\u2010km run can produce delayed increases in fluid at the ankle region, with the largest changes observed at 24\u2009hours. Clinicians should account for recent physical activity when performing and interpreting ultrasound findings, as exercise may increase the prevalence of detectable fluid at certain sites. However, as the final assessment was performed at 24\u2009hours, the full time course of these changes remains to be determined.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/pmrj.70190","type":"journal-article","created":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T21:45:54Z","timestamp":1785102354000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ultrasound evaluation of joint and bursal fluid changes after a 5\u2010km run in healthy adults"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4403-8217","authenticated-orcid":false,"given":"Jakub","family":"Ja\u010disko","sequence":"first","affiliation":[{"name":"Department of Rehabilitation and Sports Medicine, Second Faculty of Medicine Charles University and University Hospital Motol Prague Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Busch","sequence":"additional","affiliation":[{"name":"Department of Health and Human Kinetics Ohio Wesleyan University Delaware Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nat\u00e1lie","family":"Proch\u00e1zkov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation and Sports Medicine, Second Faculty of Medicine Charles University and University Hospital Motol Prague Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levent","family":"\u00d6z\u00e7akar","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine Hacettepe University Medical School Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,26]]},"reference":[{"issue":"5","key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1177\/1759720X12442112","article-title":"Role of diagnostic ultrasound in the assessment of musculoskeletal diseases","volume":"4","author":"Patil P","year":"2012","journal-title":"Ther Adv Musculoskelet Dis"},{"issue":"4","key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/s00256-017-2577-x","article-title":"Ultrasound evaluation of bursae: anatomy and pathological appearances","volume":"46","author":"Ruangchaijatuporn T","year":"2017","journal-title":"Skeletal Radiol"},{"key":"e_1_2_10_4_1","doi-asserted-by":"crossref","DOI":"10.1177\/1759720X221111610","article-title":"Changes in ultrasound imaging of joints, entheses, bursae and tendons 24 and 48 h after adjusted weight training","volume":"14","author":"Schreiner 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reference values for musculoskeletal ultrasonography","volume":"63","author":"Schmidt WA","year":"2004","journal-title":"Ann Rheum Dis"},{"issue":"5","key":"e_1_2_10_13_1","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.2214\/ajr.180.5.1801431","article-title":"Prevalence and size of meniscal cysts, ganglionic cysts, synovial cysts of the popliteal space, fluid\u2010filled bursae, and other fluid collections in asymptomatic knees on MR imaging","volume":"180","author":"Tschirch FTC","year":"2003","journal-title":"Am J Roentgenol"},{"issue":"4","key":"e_1_2_10_14_1","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/00004728-200407000-00020","article-title":"The deep infrapatellar Bursa: prevalence and morphology on routine magnetic resonance imaging of the knee","volume":"28","author":"Aydingoz U","year":"2004","journal-title":"J Comput Assist 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