{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T10:54:07Z","timestamp":1790938447087,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:00:00Z","timestamp":1790899200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:00:00Z","timestamp":1790899200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PM&amp;R"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Although high\u2010quality systematic reviews (SRs) could provide reliable evidence on the effectiveness of stroke rehabilitation treatments, methodological flaws may weaken their trustworthiness. This study aimed to evaluate the methodological quality of an up\u2010to\u2010date sample of SRs on stroke rehabilitation treatments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Literature survey<\/jats:title>\n                    <jats:p>A comprehensive search was conducted in four electronic databases (MEDLINE, EMBASE, PsycINFO, and Cochrane Database of Systematic Reviews) for SRs published between January 2021 and September 2023. Eligible SRs focused on randomized controlled trials and included at least one meta\u2010analysis assessing the effectiveness of stroke rehabilitation treatments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>After systematic screening, bibliographical data were extracted from included SRs using a predesigned form. The methodological quality was assessed using the 16\u2010item A MeaSurement Tool to Assess systematic Reviews 2 (AMSTAR 2) instrument. Associations between characteristics and methodological quality were examined using Kruskal\u2013Wallis rank test, Spearman's rank correlation coefficient, and multivariable logistic regression models. Meta\u2010analysis was not performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Synthesis<\/jats:title>\n                    <jats:p>A total of 140 SRs were appraised. Only two (1.4%) SRs were rated as having high overall methodological quality. The remaining SRs were rated as moderate (n = 2, 1.4%), low (n = 6, 4.3%), or critically low quality (n = 130, 92.9%). Cochrane SRs, SRs led by a corresponding author from the United States or Europe, SRs supported by European funding or those without funding support, SRs reporting intervention harms, and SRs published in journals with higher journal impact factors had a higher overall methodological quality than their counterparts. Only 4.3% of SRs conducted a comprehensive literature search, 12.9% provided a list of excluded studies with justifications, 7.1% explained study design selection for inclusion, 10.7% described the included primary studies in adequate detail, and 7.9% reported funding sources of primary studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The methodological quality of SRs on stroke rehabilitation treatment is unsatisfactory. Findings of this study can shed light on potential areas of methodological improvements for future review authors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pmrj.70202","type":"journal-article","created":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T10:01:50Z","timestamp":1790935310000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Methodological quality of systematic reviews on treatments in stroke rehabilitation: A cross\u2010sectional study"],"prefix":"10.1002","author":[{"given":"Yin Ting","family":"Chan","sequence":"first","affiliation":[{"name":"The Jockey Club School of Public Health and Primary Care The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheung Yuen","family":"Siu","sequence":"additional","affiliation":[{"name":"School of Chinese Medicine Hong Kong Baptist University  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung Hei","family":"Mak","sequence":"additional","affiliation":[{"name":"The Jockey Club School of Public Health and Primary Care The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0525-2621","authenticated-orcid":false,"given":"Fai Fai","family":"Ho","sequence":"additional","affiliation":[{"name":"School of Chinese Medicine The Chinese University of Hong Kong  Hong Kong China"},{"name":"School of Nursing The Hong Kong Polytechnic University  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7337-9005","authenticated-orcid":false,"given":"Betty Huan","family":"Wang","sequence":"additional","affiliation":[{"name":"The Jockey Club School of Public Health and Primary Care The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire Chenwen","family":"Zhong","sequence":"additional","affiliation":[{"name":"The Jockey Club School of Public Health and Primary Care The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisy Dexing","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Jockey Club School of Public Health and Primary Care The Chinese University of Hong Kong  Hong Kong China"},{"name":"School of Nursing The Hong Kong Polytechnic University  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5947-4492","authenticated-orcid":false,"given":"Vincent Chi Ho","family":"Chung","sequence":"additional","affiliation":[{"name":"The Jockey Club School of Public Health and Primary Care The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,2]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0b013e318296aeca"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31179-X"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(24)00642\u20101"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(24)00369-7"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2022.1520"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(23)00277-6"},{"key":"e_1_2_10_8_1","unstructured":"World Health Organization.Stroke 2025. 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