{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T11:11:30Z","timestamp":1790334690233,"version":"4.1.0"},"reference-count":53,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100009389","name":"Stiftelsen Promobilia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009389","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010814","name":"Stiftelsen f\u00f6r Bist\u00e5nd \u00e5t R\u00f6relsehindrade i Sk\u00e5ne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010814","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008590","name":"STROKE-Riksf\u00f6rbundet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008590","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1R01\u2010NS114045"],"award-info":[{"award-number":["1R01\u2010NS114045"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["PM&R"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Although fatigue is common after stroke, there is limited knowledge about gender\u2010specific differences, fatigue severity, impact on functioning, and how fatigue changes over time. With advanced stroke treatments and a higher proportion of mild strokes, updated knowledge about this condition is important.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To investigate the occurrence, severity, and impact of fatigue among men and women at 3 and 12 months after first\u2010ever ischemic stroke, including changes over time and differences between the genders.<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Prospective observational design.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n University hospital setting.<\/jats:p>\n <\/jats:sec>\n \n Participants<\/jats:title>\n A total of 268 persons (91 women) with first ever ischemic stroke (median age 73 years).<\/jats:p>\n <\/jats:sec>\n \n Main outcome measure<\/jats:title>\n The 10\u2010item Swedish version of the Fatigue Assessment Scale (S\u2010FAS) with scores ranging from 10 to 50; higher scores indicating more fatigue.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Significantly more women than men reported fatigue (ie, S\u2010FAS scores \u226524) at 3\u2009months (46% vs. 30%;\n p<\/jats:italic>\n \u2009=\u2009.013) and 12\u2009months (42% vs. 28%;\n p<\/jats:italic>\n \u2009=\u2009.036). Moderate fatigue (S\u2010FAS scores 24\u201335) was most common in both genders and at both time points. Fatigue had a similar negative impact on functioning in both men and women; the most frequent reported problems were being troubled by fatigue, getting tired very quickly, and doing few things during the day. Overall, total S\u2010FAS scores decreased significantly between 3 and 12\u2009months among both men (median 31 vs. 27,\n p<\/jats:italic>\n \u2009=\u2009.037) and women (median 30 vs. 27,\n p<\/jats:italic>\n \u2009=\u2009.007), although individual variations occurred.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Fatigue was common among people with first\u2010ever ischemic stroke, particularly in women. Although fatigue decreased over the first year, both men and women struggled with persistent fatigue which impacted their functioning negatively. To provide person\u2010centered interventions and reduce the burden of fatigue after stroke, clinicians should reassess not only the occurrence of fatigue but also its severity and consequences over time.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/pmrj.70224","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T10:57:41Z","timestamp":1790333861000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Fatigue in men and women 3 and 12\u2009months after ischemic stroke: Occurrence, severity, impact on functioning, and changes over time"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-5473-2532","authenticated-orcid":false,"given":"Sara","family":"Brycke","sequence":"first","affiliation":[{"name":"Department of Health Sciences Lund University Lund Sweden"},{"name":"Department of Neurology, Rehabilitation Medicine, Memory Disorders and Geriatrics Sk\u00e5ne University Hospital Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5931-5640","authenticated-orcid":false,"given":"Anna","family":"Norlander","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Lund University Lund Sweden"},{"name":"Department of Neurology, Rehabilitation Medicine, Memory Disorders and Geriatrics Sk\u00e5ne University Hospital Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik Blennow","family":"Nordstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Neurology, Rehabilitation Medicine, Memory Disorders and Geriatrics Sk\u00e5ne University Hospital Lund Sweden"},{"name":"Department of Clinical Sciences Lund, Neurology Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arne G.","family":"Lindgren","sequence":"additional","affiliation":[{"name":"Department of Neurology, Rehabilitation Medicine, Memory Disorders and Geriatrics Sk\u00e5ne University Hospital Lund Sweden"},{"name":"Department of Clinical Sciences Lund, Neurology Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9249-9421","authenticated-orcid":false,"given":"Christina","family":"Brog\u00e5rdh","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Lund University Lund Sweden"},{"name":"Department of Neurology, Rehabilitation Medicine, Memory Disorders and Geriatrics Sk\u00e5ne University Hospital Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"Socialstyrelsen.Nationella riktlinjer f\u00f6r v\u00e5rd vid stroke: st\u00f6d f\u00f6r styrning och ledning. 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