{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T16:40:30Z","timestamp":1783528830472,"version":"3.55.0"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T00:00:00Z","timestamp":1620691200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Paediatric and Neonatal Pain"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We aimed to compare ratings of self\u2010reported and parent\u2010reported pain sensitivity between early preterm (EP), moderately\u2010late preterm (MLP), and full\u2010term (FT) adolescents. For EP adolescents, we aimed to determine whether pain sensitivity was associated with early\u2010life events. EP (n\u00a0=\u00a068, response rate 47.4%), MLP (n\u00a0=\u00a0128, response rate 33.0%), and FT (n\u00a0=\u00a078, response rate 31.1%) adolescents and their parents (n\u00a0=\u00a0277) answered an author\u2010generated question on pain sensitivity at 14\u201015\u00a0years of age within a community\u2010based cohort study. Differences between groups were determined using the chi\u2010square test for trends. For EP adolescents, we assessed associations of treatment modalities (inotrope treatment, mechanical ventilation, and C\u2010section) and neonatal morbidities (sepsis\/necrotizing enterocolitis, small\u2010for\u2010gestational age status, asphyxia, and cerebral pathologies) with adolescent pain sensitivity using logistic regression analyses. Increased pain sensitivity was reported by 18% of EP adolescents, compared with 12% of MLP adolescents, and 7% of FT adolescents (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.033). Parent\u2010reported pain sensitivity did not differ by gestational age group. For EP adolescents, inotrope treatment was associated with increased pain sensitivity (odds ratio, 5.00, 95% confidence interval, 1.23\u201020.4, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.025). No other neonatal treatment modalities or morbidities were associated with pain sensitivity in adolescence. In conclusion, we observed higher proportions of increased pain sensitivity for EP and MLP adolescents. Physicians treating preterm adolescents should be aware of altered pain sensitivity.<\/jats:p>","DOI":"10.1002\/pne2.12053","type":"journal-article","created":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T18:24:10Z","timestamp":1620757450000},"page":"59-67","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Self\u2010reported sensitivity to pain in early and moderately\u2010late preterm\u2010born adolescents: A community\u2010based cohort study"],"prefix":"10.1002","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2706-0372","authenticated-orcid":false,"given":"Nienke H.","family":"van Dokkum","sequence":"first","affiliation":[{"name":"Department of Pediatrics Division of Neonatology Beatrix Children\u2019s Hospital, University Medical Center Groningen, University of Groningen Groningen the Netherlands"},{"name":"Department of Health Sciences University Medical Center Groningen, University of Groningen Groningen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlou L. 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Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(18)30451-0"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2017.08.020"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2009.115"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2006.02.006"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2010.01762.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2012.04423.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2011.300131"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001939"},{"key":"e_1_2_8_10_1","first-page":"e0025","article-title":"Neonatal pain in very preterm infants: long\u2010term effects on brain, 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