{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:39:49Z","timestamp":1760297989542},"reference-count":35,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2008,7,22]],"date-time":"2008-07-22T00:00:00Z","timestamp":1216684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective:<\/jats:italic> Women who carry a genetic mutation for hereditary breast\/ovarian cancer (BRCA1 or BRCA2) are at high risk to develop cancer. A positive genetic test result also has implications for a BRCA1\/2 carrier's offspring who each have a 50% chance of inheriting the mutation. The dissemination of BRCA1\/2\u2010related information by carriers to offspring is not well understood. Our study examines the experiences of BRCA1\/2 carriers in communicating genetic information to their offspring using a grounded theory approach.<\/jats:p><jats:p><jats:italic>Methods:<\/jats:italic> Qualitative data were obtained from a multi\u2010site group therapy trial for BRCA1\/2 carriers with primary themes identified and coded using the constant comparison technique and verified by team members.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> Female participants had a mean age of 45.4 years, 83% were married, 71% had children (ranging from ages 2 to 30 years) and 45.9% had a prior diagnosis of cancer. Dissemination of genetic information by BRCA1\/2 carriers to their offspring was described as a process involving several distinct phases with specific challenges within each phase. Several themes were identified including dilemmas on \u2018if\u2019 and \u2018when\u2019 to disclose to offspring, concerns should offspring receive a positive test result for BRCA1\/2, dilemmas around feeling a need to protect versus the need to inform, and women as being the primary communicators.<\/jats:p><jats:p><jats:italic>Conclusion:<\/jats:italic> These findings have implications for genetic counselling as well as follow\u2010up. 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