{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T01:45:06Z","timestamp":1774489506443,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2008,7,11]],"date-time":"2008-07-11T00:00:00Z","timestamp":1215734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2009,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective<\/jats:italic>: The present study prospectively assessed the influence of medical, socio\u2010demographic, psychological, and lifestyle variables on physical, social\/family, emotional, functional well\u2010being and colorectal cancer\u2010specific concerns in a population\u2010based sample of colorectal cancer survivors.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>: Participants (<jats:italic>n<\/jats:italic>=1822) were assessed at 6 and 24 months post\u2010diagnosis. Predictor variables assessed at 6 months included socio\u2010demographic and medical variables, symptoms\/side\u2010effects, body mass index, physical activity, optimism, social support, and cancer threat appraisal. Quality of life (QOL) was assessed at 6 and 24 months post\u2010diagnosis using the Functional Assessment of Cancer Therapy \u2010 Colorectal (FACT\u2010C).<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>: For each QOL subscale and for the overall FACT\u2010C scale, 6 month scores were the strongest predictor of QOL scores at 24 months post\u2010diagnosis (e.g. <jats:italic>\u03b2<\/jats:italic>=0.447, <jats:italic>p<\/jats:italic> &lt; 0.001 for overall QOL). Socio\u2010demographic, medical, and psychosocial variables, but not lifestyle variables, differentially predicted domain specific QOL. Only cancer threat appraisal was associated with all five QOL domains.<\/jats:p><jats:p><jats:italic>Conclusion<\/jats:italic>: Cancer threat appraisal presents as a potentially modifiable variable for interventions seeking to improve QOL. Symptom management and lifestyle strategies to ameliorate the effects of co\u2010morbidities, disease stage and troublesome symptoms such as faecal incontinence on QOL should also be included. Copyright \u00a9 2008 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/pon.1388","type":"journal-article","created":{"date-parts":[[2008,7,24]],"date-time":"2008-07-24T15:48:38Z","timestamp":1216914518000},"page":"216-220","source":"Crossref","is-referenced-by-count":51,"title":["Antecedents of domain\u2010specific quality of life after colorectal cancer"],"prefix":"10.1002","volume":"18","author":[{"given":"Suzanne K.","family":"Steginga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brigid M.","family":"Lynch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Hawkes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeff","family":"Dunn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Aitken","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,7,11]]},"reference":[{"issue":"9","key":"e_1_2_1_2_2","first-page":"1395","article-title":"Cancer survivors and quality of life: a critical review of the literature","volume":"27","author":"Zebrack B","year":"2000","journal-title":"Oncol Nurs Forum"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1586\/14737140.3.4.493"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.74.5.797"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(03)00514-2"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.24.5.508"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-006-0709-9"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2002.05694.x"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.47.4.198"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2354.1996.tb00237.x"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-007-9016-6"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1006"},{"key":"e_1_2_1_13_2","volume-title":"The Active Australia Survey: A Guide and Manual for Implementation, Analysis and Reporting","author":"Australian Institute of Health and Welfare","year":"2003"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.67.6.1063"},{"issue":"2","key":"e_1_2_1_15_2","first-page":"79","article-title":"Development of a Brief Social Support Questionnaire","volume":"16","author":"Siegert R","year":"1987","journal-title":"N Z J Psychol"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0277-9536(94)00174-R"},{"key":"e_1_2_1_17_2","volume-title":"FACIT Manual. 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