{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T16:00:23Z","timestamp":1788192023873,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2008,12,5]],"date-time":"2008-12-05T00:00:00Z","timestamp":1228435200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2009,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective<\/jats:italic>: Various studies have demonstrated that neuropsychological deficits are potential side\u2010effects of adjuvant therapy in breast cancer patients. To date, little is known about the long\u2010term development of these deficits and their implications for patients' everyday life.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>: Within the framework of an intervention study, 90 breast cancer patients after adjuvant chemotherapy were examined at three measurement points. The focus of this article is on the cognitive status at the last measurement point (on average, 9 months after the end of oncological therapy) and, in particular, on the correlations between subjective self\u2010appraisal and neuropsychological test results.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>: Although the prevalence of neuropsychological deficits significantly decreased as time elapsed after the end of oncological therapy, 21% of our sample group still displayed indications of clinically relevant long\u2010term cognitive deficits. A sub\u2010group of severely affected patients showed specific deficits in verbal\u2010semantic memory and judged their everyday cognitive performance as being extremely poor.<\/jats:p><jats:p><jats:italic>Conclusion<\/jats:italic>: The identification of verbal\u2010semantic memory as a specific problem area has important implications on the planning of future studies with regard to both the examination of underlying pathophysiological mechanisms and the specific effects of these deficits on patients' self\u2010appraisal. Copyright \u00a9 2008 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/pon.1472","type":"journal-article","created":{"date-parts":[[2008,12,5]],"date-time":"2008-12-05T13:45:28Z","timestamp":1228484728000},"page":"775-782","source":"Crossref","is-referenced-by-count":72,"title":["Cognitive deficits as long\u2010term side\u2010effects of adjuvant therapy in breast cancer patients: \u2018subjective\u2019 complaints and \u2018objective\u2019 neuropsychological test results"],"prefix":"10.1002","volume":"18","author":[{"given":"J.","family":"Weis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Poppelreuter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. 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