{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T09:46:03Z","timestamp":1768556763028,"version":"3.49.0"},"reference-count":41,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2010,10,27]],"date-time":"2010-10-27T00:00:00Z","timestamp":1288137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Objective<\/jats:italic>: Arm morbidity post\u2010breast cancer surgery is increasingly being recognized as a chronic problem for some women following breast cancer surgery. The purpose of this study was to examine demographic, disease, and treatment\u2010related predictors of a comprehensive array of chronic arm morbidity (pain, lymphedema, functional disability, and range of motion) post\u2010breast cancer surgery.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>: Women (<jats:italic>n<\/jats:italic>=316) with a non\u2010metastatic primary diagnosis of breast cancer were accrued from cancer centers in four Canadian cities. Patients completed a clinical assessment and measures of arm morbidity at 6\u201312 months post\u2010breast cancer surgery. The independent variables in the MANOVA to predict arm morbidity included: Lymph node management type, number of axillary nodes dissected, type of surgery, disease stage, presence of post\u2010operative infection, radiation to the axilla, body mass index (BMI), assessment time post\u2010surgery, education, and partner status.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>: Pain was significantly predicted by axillary lymph node management, lack of a partner, and post\u2010operative infection; lymphedema by axillary lymph node management, number of axillary nodes dissected, radiation to the axilla, and having a modified radical mastectomy; functional disability by post\u2010operative infection and high BMI; and restricted external rotation by axillary lymph node management, low educational attainment, and advanced disease.<\/jats:p><jats:p><jats:italic>Conclusion<\/jats:italic>: Comprehensive behavioral management and rehabilitation programs are needed to treat arm morbidity following breast cancer surgery. These programs should address the full scope of symptoms and associated psychosocial and functional sequelae. Copyright \u00a9 2010 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/pon.1685","type":"journal-article","created":{"date-parts":[[2010,1,22]],"date-time":"2010-01-22T13:10:34Z","timestamp":1264165834000},"page":"1205-1212","source":"Crossref","is-referenced-by-count":48,"title":["Predictors of arm morbidity following breast cancer surgery"],"prefix":"10.1002","volume":"19","author":[{"given":"Thomas F.","family":"Hack","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Winkle B.","family":"Kwan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roanne L.","family":"Thomas\u2010MacLean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Towers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baukje","family":"Miedema","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Tilley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Chateau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,10,27]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.16.4731"},{"key":"e_1_2_6_3_2","first-page":"73","article-title":"Lymphedema following breast cancer treatment, including sentinel lymph node biopsy","volume":"37","author":"Armer J","year":"2004","journal-title":"Lymphology"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-007-9593-3"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1999.17.1.143"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000245472.47748.ec"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djj158"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.03.228"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11545"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1188\/08.ONF.65-71"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2006.05.013"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.09.018"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2005.11.008"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/PPO.0b013e31817fbe5e"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/93.2.96"},{"key":"e_1_2_6_16_2","first-page":"185","article-title":"Disability, psychological distress and quality of life in breast cancer survivors with arm lymphedema","volume":"39","author":"Pyszel A","year":"2006","journal-title":"Lymphology"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-005-0810-y"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1573"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-008-0065-y"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-008-9863-8"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000184210.68646.77"},{"key":"e_1_2_6_22_2","first-page":"32","article-title":"Lymphedema: pathogenesis, prevention, and treatment","volume":"5","author":"Marcks P","year":"1997","journal-title":"Cancer Pract"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(75)90044-5"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002820-200505000-00007"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-005-5991-z"},{"key":"e_1_2_6_26_2","first-page":"84","article-title":"The diagnosis and treatment of peripheral lymphedema. 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