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The purpose of this focussed narrative review was to summarise this research and present the key lessons for clinicians and researchers working in psychosocial oncology.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>: We searched for studies assessing the utility of screening in primary care in seven electronic bibliographic databases (CENTRAL, CINAHL, Embase, HMIC, Medline, PsycINFO, Web of Knowledge) from inception to December 2010. Results were reviewed and summarised into key areas.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>: We found that research could be distilled into the following key learning points. (1) Primary care is an important partner in psychosocial care. (2) Both over and under detection are problematic. (3) Barriers to identification involve patient and clinician factors. (4) Acceptability of screening is critical to implementation. (5) Underserved groups need special attention in screening. (6) Patient\u2013clinician trust is an important modifiable variable. (7) Greater contact influences detection. (8) Clinician confidence\/skills influence screening success and subsequent action. (9) Training may improve confidence but effects upon long\u2010term outcomes are modest. (10) Screening is generally ineffective without aftercare.<\/jats:p><jats:p><jats:italic>Conclusions<\/jats:italic>: Primary care has shown largely what does not work in relation to screening. Namely relying on clinicians' unassisted judgement without infrastructural support, using over\u2010complex scales with low acceptability, looking for depression alone, using screening without linked treatment, treating in the absence of follow\u2010up and failing to engage patients in their own care. These pitfalls can and should be avoided in psychosocial oncology. 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