{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T08:06:18Z","timestamp":1789718778911,"version":"4.0.1"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,5,14]],"date-time":"2012-05-14T00:00:00Z","timestamp":1336953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Institute of Health","award":["NCI R01CA122934"],"award-info":[{"award-number":["NCI R01CA122934"]}]},{"name":"National Institute on Aging Career Development","award":["K01 AG022033"],"award-info":[{"award-number":["K01 AG022033"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The present study examined the long\u2010term cognitive implications of cancer treatment among breast cancer survivors aged 65\u2009years and older to better understand the long term implications of cancer treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010seven women survivors were compared with 30 healthy older female adult comparisons, matched in terms of age and education, with no history of cancer. Cancer survivors were also compared on the basis of treatment intervention, involving chemotherapy (<jats:italic>n<\/jats:italic>\u2009=\u200927) versus local therapy through surgery and radiation (<jats:italic>n<\/jats:italic>\u2009=\u200930).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>As a group, the breast cancer survivors scored lower on measures of general cognitive function, working memory, psychomotor speed, and executive function when compared with the normal comparisons. Among the cancer survivors, those who received local therapy scored lower than the other survivors and normal comparisons on measures of verbal learning, visual perception and construction, as well as visual attention and short\u2010term retention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings suggest that cognitive outcomes may involve greater age\u2010related deficits among older cancer survivors compared with matched healthy subjects. 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