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A randomised controlled trial tested whether writing about the patient's diagnosis and treatment of ovarian cancer using the Guided Disclosure Protocol (GDP) is effective in reducing perceived stress and improving quality of life (QoL) in ovarian cancer couples. The study also tested two theories that may account for beneficial effects of written emotional disclosure, the cognitive processing hypothesis and the social interaction hypothesis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients and their partners (<jats:italic>N<\/jats:italic>\u2009=\u2009102 couples) were randomised to write at home for 15\u2009min a day over 3\u2009days about the patient's diagnosis and treatment using the GDP or what the patient did the previous day (control). Couples were assessed at baseline, 3\u2010 and 6\u2010month follow\u2010ups on the primary outcomes of perceived stress and QoL and secondary outcomes of intrusive thoughts (testing the cognitive processing hypothesis) and illness\u2010related couple communication (testing the social interaction hypothesis).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no main effects for any outcomes. However, in patients, the GDP improved QoL if illness\u2010related couple communication improved and buffered the effect of intrusive thoughts on perceived stress.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The GDP might benefit patients in certain circumstances, through changes in communication (in line with the social interaction hypothesis). Further research is needed to determine whether patients benefit from interventions to improve illness\u2010related couple communication and under which conditions. Copyright \u00a9 2013 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.3280","type":"journal-article","created":{"date-parts":[[2013,3,15]],"date-time":"2013-03-15T18:35:40Z","timestamp":1363372540000},"page":"2262-2269","source":"Crossref","is-referenced-by-count":33,"title":["Written emotional disclosure for women with ovarian cancer and their partners: randomised controlled trial"],"prefix":"10.1002","volume":"22","author":[{"given":"Emily","family":"Arden\u2010Close","sequence":"first","affiliation":[{"name":"Centre for Applications of Health Psychology Academic Unit of Psychology, University of Southampton  Southampton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yori","family":"Gidron","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy Vrije Universiteit Brussel  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Bayne","sequence":"additional","affiliation":[{"name":"Ovacome, The UK Ovarian Cancer Charity  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rona","family":"Moss\u2010Morris","sequence":"additional","affiliation":[{"name":"Psychology Department, Institute of Psychiatry King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,3,15]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Office for National Statistics.Statistical Bulletin: Cancer survival in England: one\u2010year and five\u2010year survival for 21 common cancers by sex and age April2011. 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