{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T07:19:36Z","timestamp":1776410376082,"version":"3.51.2"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,9,11]],"date-time":"2015-09-11T00:00:00Z","timestamp":1441929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"German Federal Ministry of Education and Research","award":["01 ZP 0505"],"award-info":[{"award-number":["01 ZP 0505"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>This study examined the frequency of psychiatric co\u2010morbidity in patients with breast cancer, its changes over time and predictors for these changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a prospective study with measurements before surgery (t1, baseline), 1\u00a0month (t2) and 8\u00a0months thereafter (t3) using the Patient Health Questionnaire, we examined the course of psychiatric co\u2010morbidity in breast cancer patients. The co\u2010morbidity courses were grouped into healthy (no co\u2010morbidity during the study), acute (co\u2010morbidity at t1 and\/or t2, but not at t3), emerging (no co\u2010morbidity at t1, but at t3) and chronic (co\u2010morbidity at t1 and t3).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 598 participants, 19% had acute, 10% emerging and 9% chronic psychiatric co\u2010morbidity. Acute co\u2010morbidity was more common in patients with poor quality of life (odds ratio (OR) 9.6, 95% confidence interval (CI) 4.4\u201320.8) and somatic co\u2010morbidity (OR 3.8, CI 1.1\u201312.4). Patients who perceived support from their doctors had acute co\u2010morbidity less frequently (OR 0.7, CI 0.5\u20131.0). Emerging co\u2010morbidity occurred more often in younger patients (OR 2.4, CI 1.2\u20134.7) and in patients with another cancer in their own (OR 2.0, CI 1.1\u20133.9) or family (OR 2.1, CI 1.1\u20134.3) histories, less often in patients with support from doctors (OR 0.6, CI 0.4\u20131.0). Chronic co\u2010morbidity was related to poor quality of life (OR 12.1, CI 3.6\u201339.9).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We found acute and emerging psychiatric co\u2010morbidities less often in patients who reported having a supportive doctor\u2013patient relationship. Patients that require psycho\u2010oncological support often have poor quality of life and have experienced cancer before. Copyright \u00a9 2015 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.3978","type":"journal-article","created":{"date-parts":[[2015,9,11]],"date-time":"2015-09-11T16:43:15Z","timestamp":1441989795000},"page":"590-596","source":"Crossref","is-referenced-by-count":11,"title":["The course of psychiatric co\u2010morbidity in patients with breast cancer \u2013 results from the prospective multi\u2010centre BRENDA II study"],"prefix":"10.1002","volume":"25","author":[{"given":"Susanne","family":"Singer","sequence":"first","affiliation":[{"name":"Institute of Medical Biostatistics, Epidemiology and Informatics University Medical Centre, Johannes Gutenberg University Mainz  Mainz Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas","family":"Schwentner","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics University of Ulm  Ulm Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reyn","family":"van Ewijk","sequence":"additional","affiliation":[{"name":"Institute of Medical Biostatistics, Epidemiology and Informatics University Medical Centre, Johannes Gutenberg University Mainz  Mainz Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Blettner","sequence":"additional","affiliation":[{"name":"Institute of Medical Biostatistics, Epidemiology and Informatics University Medical Centre, Johannes Gutenberg University Mainz  Mainz Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Achim","family":"W\u00f6ckel","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics University of W\u00fcrzburg  W\u00fcrzburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thorsten","family":"K\u00fchn","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Hospital Esslingen  Esslingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Felberbaum","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Hospital Kempten  Kempten Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix","family":"Flock","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Hospital Memmingen  Memmingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Janni","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics University of Ulm  Ulm Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for the BRENDA Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38343.670868.D3"},{"key":"e_1_2_8_3_1","article-title":"Prevalence and long\u2010term course of psychiatric disorders in cancer patients: a pilot study","volume":"5","author":"Bringmann H","year":"2008","journal-title":"Psychosoc Med"},{"key":"e_1_2_8_4_1","volume-title":"PHQ\u2010D Manual","author":"L\u00f6we B","year":"2002"},{"key":"e_1_2_8_5_1","volume-title":"Structured Clinical Interview for DSM\u2010IV Axis I Disorders (SCID\u2010I), Clinician Version","author":"First M","year":"1997"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01840834"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1634956"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/85.5.365"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(00)00447-0"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02602306"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10389-004-0034-5"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.56.0086"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-985643"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3282"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70002-X"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdp515"},{"key":"e_1_2_8_17_1","first-page":"1","article-title":"Waiting times in psychotherapy","volume":"6","author":"Bundespsychotherapeutenkammer","year":"2011","journal-title":"BPtK Spezial"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-952034"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.12.139"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.08.149"},{"key":"e_1_2_8_21_1","doi-asserted-by":"crossref","unstructured":"SchwentnerL SingerS vanEwijkR et al.Frequency and reasons for deviation from therapy decisions in patients with primary breast cancer initially intended to receive chemotherapy \u2013 results from the German prospective multi\u2010center study BRENDA II.San Antonio Breast Cancer Conference2014: P3\u201009\u201006.","DOI":"10.1158\/1538-7445.SABCS14-P3-09-06"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1159\/000381933"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2354.2009.01117.x"},{"key":"e_1_2_8_24_1","volume-title":"Handbook of Psychooncology","author":"Holland J","year":"1989"},{"key":"e_1_2_8_25_1","volume-title":"Introduction into Psycho\u2010Oncology","author":"Meerwein F","year":"1981"},{"key":"e_1_2_8_26_1","volume-title":"Mourning and Melancholia","author":"Freud S","year":"1916"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1478951512000491"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1375\/S0814723X00001923"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3445"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00278-005-0466-6"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00278-011-0859-7"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3145"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2009.08.004"}],"container-title":["Psycho-Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpon.3978","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pon.3978","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T02:53:08Z","timestamp":1696474388000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pon.3978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,11]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["10.1002\/pon.3978"],"URL":"https:\/\/doi.org\/10.1002\/pon.3978","archive":["Portico"],"relation":{},"ISSN":["1057-9249","1099-1611"],"issn-type":[{"value":"1057-9249","type":"print"},{"value":"1099-1611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,11]]}}}