{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T10:11:47Z","timestamp":1788084707399,"version":"build-2784847793"},"reference-count":40,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T00:00:00Z","timestamp":1493164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Foundation Alpe d'Huzes and the Dutch Cancer Society","award":["KUN 2011-5077"],"award-info":[{"award-number":["KUN 2011-5077"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Lung cancer patients report among the highest distress rates of all cancer patients. Partners report similar distress rates. The present study examined the effectiveness of additional mindfulness\u2010based stress reduction (care as usual [CAU]\u00a0+\u00a0MBSR) versus solely CAU to reduce psychological distress in lung cancer patients and\/or their partners.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a multicentre, parallel\u2010group, randomized controlled trial. Mindfulness\u2010based stress reduction is an 8\u2010week group\u2010based intervention, including mindfulness practice and teachings on stress. Care as usual included anticancer treatment, medical consultations, and supportive care. The primary outcome was psychological distress. Secondary outcomes included quality of life, caregiver burden, relationship satisfaction, mindfulness skills, self\u2010compassion, rumination, and posttraumatic stress symptoms. Outcomes were assessed at baseline, post\u2010intervention, and 3\u2010month follow\u2010up. Linear mixed modeling was conducted on an intention\u2010to\u2010treat sample. Moderation (gender, disease stage, baseline distress, participation with\/without partner) and mediation analyses were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 31 patients and 21 partners were randomized to CAU\u00a0+\u00a0MBSR and 32 patients and 23 partners to CAU. After CAU\u00a0+\u00a0MBSR patients reported significantly less psychological distress (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.008, <jats:italic>d\u00a0=<\/jats:italic>\u00a0.69) than after CAU. Baseline distress moderated outcome: those with more distress benefitted most from MBSR. Additionally, after CAU\u00a0+\u00a0MBSR patients showed more improvements in quality of life, mindfulness skills, self\u2010compassion, and rumination than after CAU. In partners, no differences were found between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings suggest that psychological distress in lung cancer patients can be effectively treated with MBSR. No effect was found in partners, possibly because they were more focused on patients' well\u2010being rather than their own.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.4430","type":"journal-article","created":{"date-parts":[[2017,3,24]],"date-time":"2017-03-24T11:23:28Z","timestamp":1490354608000},"page":"2118-2126","source":"Crossref","is-referenced-by-count":116,"title":["Mindfulness\u2010based stress reduction added to care as usual for lung cancer patients and\/or their partners: A multicentre randomized controlled trial"],"prefix":"10.1002","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8397-7674","authenticated-orcid":false,"given":"M.P.J.","family":"Schellekens","sequence":"first","affiliation":[{"name":"Department of Psychiatry Radboud University Medical Centre  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.G.M.","family":"van den Hurk","sequence":"additional","affiliation":[{"name":"Department of Pulmonary 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