{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T04:02:43Z","timestamp":1789790563682,"version":"4.0.1"},"reference-count":40,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010417","name":"University Hospital Southampton NHS Foundation Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010417","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000739","name":"University of Southampton","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000739","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011715","name":"Macmillan Cancer Support","doi-asserted-by":"publisher","award":["3546834"],"award-info":[{"award-number":["3546834"]}],"id":[{"id":"10.13039\/100011715","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Social support is acknowledged as important in cancer survivorship, but little is known about change in support after cancer diagnosis and factors associated with this, particularly in colorectal cancer. The CREW cohort study investigated social support up to 2\u00a0years following curative intent surgery for colorectal cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 871 adults recruited pre\u2010treatment from 29 UK centres 2010 to 2012 consented to follow\u2010up. Questionnaires at baseline, 3, 9, 15, and 24\u00a0months post\u2010surgery included assessments of social support (Medical Outcomes Study\u2010Social Support Survey, MOS\u2010SSS) and health\u2010related quality of life (HRQoL). Socio\u2010demographic, clinical and treatment details were collected. Longitudinal analyses assessed social support over follow\u2010up, associations with participant characteristics, and HRQoL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Around 20% were living alone and 30% without a partner. Perceived social support declined in around 29% of participants, with 8% of these reporting very low levels overall from baseline to 2\u00a0years (mean MOS\u2010SSS overall score\u00a0&lt;\u00a040 on a scale from 0 to 100). Older age, female gender, greater neighbourhood deprivation, presence of co\u2010morbidities, and rectal cancer site were significantly associated with reductions in perceived support. Poorer HRQoL outcomes (generic health\/QoL, reduced wellbeing, anxiety, and depression) were significantly associated with lower levels of social support.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Levels of social support decline following colorectal cancer diagnosis and treatment in nearly a third of patients and are an important risk factor for recovery of HRQoL. Assessment of support early on and throughout follow\u2010up would enable targeted interventions to improve recovery, particularly in the more vulnerable patient groups at risk of poorer social support.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.4556","type":"journal-article","created":{"date-parts":[[2017,11,2]],"date-time":"2017-11-02T00:12:37Z","timestamp":1509581557000},"page":"2276-2284","source":"Crossref","is-referenced-by-count":74,"title":["Social support following diagnosis and treatment for colorectal cancer and associations with health\u2010related quality of life: Results from the UK ColoREctal Wellbeing (CREW) cohort study"],"prefix":"10.1002","volume":"26","author":[{"given":"Joanne","family":"Haviland","sequence":"first","affiliation":[{"name":"Institute of Cancer Research Clinical Trials and Statistics Unit, Division of Clinical Studies The Institute of Cancer Research  London 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