{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T11:33:57Z","timestamp":1790249637889,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,4,26]],"date-time":"2018-04-26T00:00:00Z","timestamp":1524700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005972","name":"Deutsche Krebshilfe","doi-asserted-by":"publisher","award":["107465"],"award-info":[{"award-number":["107465"]}],"id":[{"id":"10.13039\/501100005972","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study provides prevalence data of mental disorders (4\u2010week, 1\u2010year, lifetime) and psychological distress in Adolescent and Young Adult (AYAs) with cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We included an AYA subsample (15 to 39\u00a0year olds; diagnosed within the last 5\u00a0years) extracted from a larger sample (4.020 cancer patients) who had been recruited for an epidemiological study across all major tumor entities\n                      <jats:bold>.<\/jats:bold>\n                      Participants were assessed with a depression screener (PHQ\u20109). Following that, 50% of the participants who scored below the cutoff of 9 and all patients who scored above were assessed using the Composite International Diagnostic Interview for Oncology (CIDI\u2010O). Patients also completed an anxiety screener (GAD\u20107).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 302 AYA (167 completed CIDI\u2010O) were identified. With regard to psychological distress, 29.5% of the AYA had increased depression symptoms (PHQ\u20109), and 20.8% had increased anxiety symptoms (GAD\u20107). Gender and age were associated with psychological distress, with women and older AYA being found to have higher distress. The 4\u2010week prevalence of mental disorders of any kind was 46.7% (95%\u2010CI:39%\u201055%). Anxiety (24.4%; 95%\u2010CI:20%\u201036%) and adjustment disorders (14.1%; 95%\u2010CI:9%\u201019%) had the highest prevalence rates. The lowest prevalence rates were reported for alcohol dependence (0.8%; 95%\u2010CI:0%\u20102%) and somatoform disorders (3.7%; 95%\u2010CI:1%\u20107%). The 1\u2010year\u2010prevalence was 55.4% (CI:47.36\u201062.64), and the lifetime\u2010prevalence was 69.5% (CI: 62.29\u201077.06).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings may sensitize clinicians to the possible presence of mental disorders in AYA. The results indicate that there is a strong need for psycho\u2010oncological interventions designed to improve mental health in AYAs with cancer at all stages of medical care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pon.4730","type":"journal-article","created":{"date-parts":[[2018,4,12]],"date-time":"2018-04-12T04:47:31Z","timestamp":1523508451000},"page":"1802-1809","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":86,"title":["Prevalence of mental disorders and psychosocial distress in German adolescent and young adult cancer patients (AYA)"],"prefix":"10.1002","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6590-5650","authenticated-orcid":false,"given":"Kristina","family":"Geue","sequence":"first","affiliation":[{"name":"Department of Medical Psychology and Medical Sociology University Medical Center Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elmar","family":"Br\u00e4hler","sequence":"additional","affiliation":[{"name":"Department of Medical Psychology and Medical Sociology University Medical Center Leipzig  Leipzig Germany"},{"name":"Department of Psychosomatic Medicine and Psychotherapy Universal Medical Center Mainz  Mainz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermann","family":"Faller","sequence":"additional","affiliation":[{"name":"Department of Medical Psychology and Psychotherapy, Medical Sociology and Rehabilitation Sciences, and Comprehensive Cancer Center Mainfranken University of W\u00fcrzburg  W\u00fcrzburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"H\u00e4rter","sequence":"additional","affiliation":[{"name":"Department and Outpatient Clinic of Medical Psychology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Schulz","sequence":"additional","affiliation":[{"name":"Department and Outpatient Clinic of Medical Psychology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim","family":"Weis","sequence":"additional","affiliation":[{"name":"Department of Psychooncology, Tumor Biology Center University Medical Center Freiburg  Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"Koch","sequence":"additional","affiliation":[{"name":"Department and Outpatient Clinic of Medical Psychology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"},{"name":"Deanery, University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans\u2010Ulrich","family":"Wittchen","sequence":"additional","affiliation":[{"name":"Institute of Clinical Psychology and Psychotherapy Technical University Dresden  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6872-9805","authenticated-orcid":false,"given":"Anja","family":"Mehnert","sequence":"additional","affiliation":[{"name":"Department of Medical Psychology and Medical Sociology University Medical Center Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,4,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28231"},{"key":"e_1_2_9_3_1","unstructured":"Robert Koch Institute (RKI).Krebs in Deutschland 2011\/2012. 10. Ausgabe. Robert Koch\u2010Institut (Hrsg) und die Gesellschaft der epidemiologischen Krebsregister in Deutschland e.V. (Hrsg).Berlin 2015 10th ed."},{"key":"e_1_2_9_4_1","unstructured":"Country of birth AYA Oncology Progress Review Group.Closing the gap: research and care imperatives for adolescents and young adults with cancer: report of the Adolescent and Young Adult Oncology Progress Review Group;2006http:\/\/www.cancer.gov\/types\/aya\/research\/ayao\u2010august\u20102006.pdf."},{"key":"e_1_2_9_5_1","unstructured":"Hilgendorf Inken;BorchmannP;EngelJ et al.Heranwachsende und junge Erwachsene: Onkopedia Leitlinien;2016.https:\/\/www.onkopedia.com\/de\/onkopedia\/guidelines\/heranwachsende\u2010und\u2010junge\u2010erwachsene\u2010aya\u2010adolescents\u2010and\u2010young\u2010adults\/@@view\/html\/index.html."},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2349"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29868"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30417"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0b013e32816ebc8c"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.publhealth.29.020907.090847"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1026\/0943-8149\/a000036"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.2147\/PROM.S51658"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29866"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.45.9222"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-010-1059-7"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3965"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28739"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.69.7946"},{"issue":"4","key":"e_1_2_9_19_1","first-page":"167","article-title":"Distress and adjustment among adolescents and young adults with cancer: an empirical and conceptual review","volume":"2","author":"Sansom\u2010Daly UM","year":"2013","journal-title":"Transl Pediatr"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29736"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-12-70"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.56.0086"},{"key":"e_1_2_9_23_1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: DSMIV\u2010TR","author":"American Psychiatric Association","year":"2009"},{"key":"e_1_2_9_24_1","unstructured":"World Health Organisation.The International Statistical Classification of Diseases and Related Health Problems ICD\u201010: Package of Volumes 1 2 and 3.Geneva Switzerland;2012."},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(03)00198-8"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(02)00237-9"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.10.1092"},{"key":"e_1_2_9_28_1","volume-title":"DIA\u2010X Interview","author":"Wittchen H","year":"1996"},{"key":"e_1_2_9_29_1","first-page":"101","article-title":"Adaptation of the Composite International Diagnostic Interview (CIDI) for the assessment of comorbid mental disorders in oncology patients: the CIDI\u2010O","volume":"64","author":"Hund B","year":"2014","journal-title":"Psychother Psychosom Med Psychol"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(94)90036-1"},{"key":"e_1_2_9_31_1","volume-title":"Mental Illness in General Health Care. An International Study","author":"\u00dcst\u00fcn T","year":"1995"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-013-0559-6"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3533"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-013-1793-8"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdp515"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1159\/000446991"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70002-X"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1309032"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1089\/jayao.2015.0035"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2015.04.003"}],"container-title":["Psycho-Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpon.4730","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pon.4730","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T13:14:20Z","timestamp":1694870060000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pon.4730"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,26]]},"references-count":39,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.1002\/pon.4730"],"URL":"https:\/\/doi.org\/10.1002\/pon.4730","archive":["Portico"],"relation":{},"ISSN":["1057-9249","1099-1611"],"issn-type":[{"value":"1057-9249","type":"print"},{"value":"1099-1611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,26]]},"assertion":[{"value":"2017-06-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}