{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:46:54Z","timestamp":1788482814427,"version":"build-2803163510"},"reference-count":39,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,9,27]],"date-time":"2018-09-27T00:00:00Z","timestamp":1538006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006636","name":"Forskningsr\u00e5det om H\u00e4lsa, Arbetsliv och V\u00e4lf\u00e4rd","doi-asserted-by":"publisher","award":["2014\u20104689"],"award-info":[{"award-number":["2014\u20104689"]}],"id":[{"id":"10.13039\/501100006636","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009107","name":"V\u00e5rdalstiftelsen","doi-asserted-by":"publisher","award":["2014\u20100098"],"award-info":[{"award-number":["2014\u20100098"]}],"id":[{"id":"10.13039\/100009107","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006313","name":"Barncancerfonden","doi-asserted-by":"publisher","award":["TJ2014\u20100050"],"award-info":[{"award-number":["TJ2014\u20100050"]}],"id":[{"id":"10.13039\/501100006313","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002794","name":"Cancerfonden","doi-asserted-by":"publisher","award":["CAN 2013\/886"],"award-info":[{"award-number":["CAN 2013\/886"]}],"id":[{"id":"10.13039\/501100002794","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007232","name":"Radiumhemmets Forskningsfonder","doi-asserted-by":"publisher","award":["161272"],"award-info":[{"award-number":["161272"]}],"id":[{"id":"10.13039\/501100007232","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>A dearth of studies focusing on young women (&lt;40\u00a0years) with breast cancer have hampered the understanding of the type, prevalence, and predictors of sexual dysfunction and reproductive concerns in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data were collected from 181 women (response rate\u00a0=\u00a060%) diagnosed with breast cancer approximately 2\u00a0years previously (age 21\u201039) using the Swedish National Quality Registry for Breast Cancer and a survey including standardized measures of sexual dysfunction, reproductive concerns, body image, and health\u2010related quality of life. Multivariable logistic binary regression analyses were used to identify predictors of sexual dysfunction and reproductive concerns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sexual dysfunction in at least one domain was reported by 68% of the women, and a high level of reproductive concerns in at least one dimension was reported by 58%. Model results showed that current endocrine treatment was a significant predictor of dysfunction related to lubrication (OR 3.8, 95% CI 1.2\u201012.1) and vaginal discomfort (OR 8.7, 95% CI 1.5\u201051.5). Negative body image was related to satisfaction with sex life (OR 1.1, 95% CI 1.0\u20101.2). A high level of reproductive concerns was predicted by a wish for (additional) children in the future (OR 3.4, 95% CI 1.1\u201010.2) and by previous chemotherapy (OR 2.5, 95% CI 1.1\u20105.9).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Sexual dysfunction and reproductive concerns are common in young women with breast cancer. Current endocrine treatment, previous chemotherapy, a negative body image, and a wish for children in the future predict higher level of problems.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pon.4886","type":"journal-article","created":{"date-parts":[[2018,9,11]],"date-time":"2018-09-11T05:34:58Z","timestamp":1536644098000},"page":"2770-2777","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":148,"title":["Sexual dysfunction and reproductive concerns in young women with breast cancer: Type, prevalence, and predictors of problems"],"prefix":"10.1002","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1406-6329","authenticated-orcid":false,"given":"Lisa","family":"Ljungman","sequence":"first","affiliation":[{"name":"Department of Women's and Children's Health Karolinska Institutet  Solna Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Ahlgren","sequence":"additional","affiliation":[{"name":"Department of Oncology, Faculty of Medicine and Health \u00d6rebro University  \u00d6rebro Sweden"},{"name":"Regional Cancer Centre, Uppsala\u2010\u00d6rebro  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena\u2010Marie","family":"Petersson","sequence":"additional","affiliation":[{"name":"Department of Neurobiology, Care Sciences and Society Karolinska Institutet  Solna Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn E.","family":"Flynn","sequence":"additional","affiliation":[{"name":"Department of Medicine Medical College of Wisconsin  Milwaukee WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Weinfurt","sequence":"additional","affiliation":[{"name":"Department of Population Health Sciences Duke University School of Medicine  Durham NC 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