{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:36:09Z","timestamp":1785418569687,"version":"3.56.0"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,11,13]],"date-time":"2019-11-13T00:00:00Z","timestamp":1573603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100013421","name":"Pink Ribbon Foundation","doi-asserted-by":"publisher","award":["2012.WO43.C158"],"award-info":[{"award-number":["2012.WO43.C158"]}],"id":[{"id":"10.13039\/100013421","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Fear of cancer recurrence (FCR) is a common consequence of surviving cancer; therefore, easily accessible self\u2010help training could help many cancer survivors deal with FCR at low costs. The CAncer REcurrence Self\u2010help Training (CAREST) trial evaluates the effectiveness of an online\u2010tailored self\u2010help training on the basis of evidence\u2010based cognitive behavioral therapy principles in breast cancer survivors. Also, possible predictors for benefitting from the online self\u2010help training were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This multicenter randomized controlled trial included 262 female breast cancer survivors, randomly assigned to either online self\u2010help training (n\u00a0=\u00a0130) or care as usual (CAU; n\u00a0=\u00a0132). Participants completed questionnaires at baseline (T0), 3\u00a0months (T1; after intervention), and 9\u00a0months (T2). The primary outcome was FCR (Fear of Cancer Recurrence Inventory Severity subscale). Both effectiveness and predictors were analyzed with latent growth curve modeling (LGCM) according to the intention\u2010to\u2010treat principle.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>LGCM showed no differences between the average latent slope in both groups (<jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup><jats:sub>1<\/jats:sub>\u00a0=\u00a0.23, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.63), suggesting that the treatments did not differ in their change in FCR over time. Moreover, no differences were found in the effects of the predictors on the latent slope in both groups (<jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup><jats:sub>1<\/jats:sub>\u00a0=\u00a0.12, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.73), suggesting that no significant predictors were found for the effect of the intervention on FCR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There was no effect of the CBT\u2010based online self\u2010help training \u201cLess fear after cancer\u201d in the current study. Therefore, we recommend adding professional support to online interventions for FCR.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.5233","type":"journal-article","created":{"date-parts":[[2019,10,9]],"date-time":"2019-10-09T05:54:50Z","timestamp":1570600490000},"page":"86-97","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["No effect of CBT\u2010based online self\u2010help training to reduce fear of cancer recurrence: First results of the CAREST multicenter randomized controlled trial"],"prefix":"10.1002","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2812-2336","authenticated-orcid":false,"given":"Sanne Jasperine","family":"van Helmondt","sequence":"first","affiliation":[{"name":"Scientific Research Department Helen Dowling Institute  Bilthoven The 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