{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T06:24:20Z","timestamp":1791095060806,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2002,1,25]],"date-time":"2002-01-25T00:00:00Z","timestamp":1011916800000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Background:<\/jats:italic> Lung cancer is a major health problem throughout the world. It is the leading cause of cancer\u2010related death in men and women in the USA, with a 5\u2010year survival rate of only 14%. It has been hypothesized that variables such as physical and social functioning, cancer\u2010related symptomatology, comorbid conditions, cell type, and treatment are valid predictors of the psychological response to a diagnosis of lung cancer.<\/jats:p><jats:p><jats:italic>Methods:<\/jats:italic> As part of a larger longitudinal study, 211 patients, 65 years of age or older, with an incident diagnosis of lung cancer, were recruited from 23 sites within a midwestern state. Repeated measures analysis of variance techniques were used to analyse how age, gender, comorbid conditions, stage of disease, cell type, as well as the time\u2010dependent variables symptoms, physical functioning, social functioning, and treatment predict depressive symptomatology at four assessments over the first year following diagnosis.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> Social functioning (<jats:italic>p<\/jats:italic>&lt;0.0001), symptoms severity (<jats:italic>p<\/jats:italic>&lt;0.0001) and radiation treatment (<jats:italic>p<\/jats:italic>=0.017) were significant predictors of depressive symptomatology, with more symptoms and more restricted social functioning generally corresponding to higher levels of depressive symptomatology. Patients who had not received radiation treatment were more depressed than those who had received treatment at least 40 days prior to the interview.<\/jats:p><jats:p><jats:italic>Conclusions:<\/jats:italic> At a clinical level of patient care, these findings mandate early identification of psychosocial difficulties experienced, an individualized symptom management plan and the application of other interventions, such as information giving, reassurance and referral to other resources. Copyright \u00a9 2002 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/pon.545","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T22:14:37Z","timestamp":1030313677000},"page":"12-22","source":"Crossref","is-referenced-by-count":77,"title":["Predictors of depressive symptomatology of geriatric patients with lung cancer\u2014a longitudinal analysis"],"prefix":"10.1002","volume":"11","author":[{"given":"M.E.","family":"Kurtz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.C.","family":"Kurtz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Stommel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.W.","family":"Given","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Given","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,1,25]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0163-8343(94)90021-3"},{"key":"e_1_2_1_3_1","volume-title":"Manual for Staging of Cancer","author":"Beahrs OH","year":"1992"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19871001)60:7<1661::AID-CNCR2820600740>3.0.CO;2-4"},{"key":"e_1_2_1_5_1","volume-title":"Methodological Issues for Health Care Surveys","author":"Cox BG","year":"1985"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0738-3991(89)90046-3"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02113-9"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19941001)74:7 <2128::AID-CNCR2820741721>3.0.CO;2-J"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1997.370"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(99)00004-5"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.2960040104"},{"key":"e_1_2_1_12_1","first-page":"13","article-title":"Staging for cancer: new developments and importance to pathology","volume":"109","author":"Henson DE","year":"1985","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_1_13_1","first-page":"1992","volume-title":"Classification of Malignant Tumors","author":"Hermanek P","year":"1992"},{"key":"e_1_2_1_14_1","first-page":"180","volume-title":"Handbook of Psychooncology","author":"Holland JC","year":"1989"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0690(18)30799-7"},{"issue":"37","key":"e_1_2_1_16_1","first-page":"8","article-title":"Depression in lung cancer: prevalence, risk factors and implications for management","volume":"4","author":"Hopwood P","year":"2000","journal-title":"Opin Topics Supportive Care Oncol"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.4.893"},{"issue":"4","key":"e_1_2_1_18_1","first-page":"253","article-title":"Psychosocial needs of older cancer patients: a pilot study abstract","volume":"5","author":"Houldin AD","year":"1996","journal-title":"MEDSURG Nurs"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-8140(93)90073-H"},{"key":"e_1_2_1_20_1","first-page":"227","volume-title":"Perspectives on Treatment and Prevention of Cancer in the Elderly","author":"Kane RA","year":"1983"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(97)00323-7"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s005200050270"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0885-3924(00)00120-2"},{"key":"e_1_2_1_24_1","first-page":"395","article-title":"The psychosocial support status of elderly cancer outpatients","volume":"120","author":"Maisiak R","year":"1983","journal-title":"Prog Clin Biol Res"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1995.03950140007002"},{"issue":"43","key":"e_1_2_1_26_1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/00005650-199303000-00006","article-title":"The MOS 36 item short form health survey (SF\u201036): II. 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