{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T08:25:58Z","timestamp":1750667158575},"reference-count":84,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2002,1,25]],"date-time":"2002-01-25T00:00:00Z","timestamp":1011916800000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This paper summarizes what is known about the diagnosis, treatment, and follow\u2010care of people with the inherited disorder multiple endocrine neoplasia type 2a (MEN2a). Several databases were searched throughout the year 2000, including MEDLINE, CINAHL, CancerLit, PsychINFO, and Dissertation Abstracts International. MEN2a is a complex disease involving cancer care and control by surgery, health maintenance, and life\u2010long observation of gene mutation carriers. Genetic testing is the standard of care, prophylactic surgery is recommended during directive counseling, and life\u2010long surveillance is encouraged for people with MEN2a. A substantial body of scientific literature describes morbidity and mortality outcomes of disease treatment, and the monitoring of multiple organ systems. Research is scant concerning the psychological consequences and social impact of the MEN2a diagnosis, treatment, and follow\u2010up. Nearly all that is known from a psycho\u2010social perspective comes from data in The Netherlands. Little is known of the psychological responses to and social consequences of genetic predisposition testing, prophylactic and curative surgery, and life\u2010long surveillance. Psycho\u2010social research is essential to provide comprehensive care for patients and family members with this disorder and it is necessary to guide the development of risk management strategies for patients with this inherited cancer syndrome. Since MEN2a has been labeled a prototype for medical genetics, information on MEN2a patient experiences may be relevant to the care of individuals with other inherited cancer syndromes. Copyright \u00a9 2002 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/pon.546","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T22:14:37Z","timestamp":1030313677000},"page":"59-73","source":"Crossref","is-referenced-by-count":4,"title":["Multiple endocrine neoplasia type 2a (MEN2a): a call for psycho\u2010social research"],"prefix":"10.1002","volume":"11","author":[{"given":"Ellen","family":"Giarelli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,1,25]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1997.tb52166.x"},{"issue":"11","key":"e_1_2_1_3_1","first-page":"114","article-title":"Pentagastrin stimulation test and early diagnosis of medullary thyroid carcinoma using an immunoradiometric assay or calcitonin: comparison with genetic screening in hereditary medullary thyroid 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