{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:58:12Z","timestamp":1791413892635,"version":"4.3.3"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T00:00:00Z","timestamp":1632787200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Providing genetic counseling and genetic testing to at\u2010risk blood relatives (cascade screening) is important for improving<jats:italic>BRCA<\/jats:italic>cancer outcomes. Intra\u2010familial communication of risk is critical for cascade screening efforts yet relatively little is known about men's role in communicating<jats:italic>BRCA<\/jats:italic>risk. We sought to examine men's coping response to their<jats:italic>BRCA<\/jats:italic>status and intra\u2010familial communication of risk to inform the development of tailored interventions that could promote cascade screening.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We employed a sequential mixed\u2010methods design. First, we measured coping response (quantitative) using the Multidimensional Impact of Cancer Risk Assessment (MICRA). MICRA scores were compared between<jats:italic>BRCA<\/jats:italic>+ men,<jats:italic>BRCA<\/jats:italic>\u2212 men and<jats:italic>BRCA<\/jats:italic>+ women. Subsequently, we used template analysis to analyze qualitative interviews exploring coping and intra\u2010familial communication of risk. The Theory of Planned Behavior (TPB) served as a guiding framework for identifying intervention targets.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:italic>BRCA<\/jats:italic>+ men (<jats:italic>n<\/jats:italic>\u00a0=\u00a036) had significantly higher levels of distress (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), uncertainty (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) and negative experiences (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05) compared to<jats:italic>BRCA<\/jats:italic>\u2212 male counterparts (<jats:italic>n<\/jats:italic>\u00a0=\u00a023).<jats:italic>BRCA<\/jats:italic>+ men had significantly lower distress (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) and uncertainty (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) than<jats:italic>BRCA<\/jats:italic>+ women (<jats:italic>n<\/jats:italic>\u00a0=\u00a0406). Qualitative analysis of in\u2010depth interviews with<jats:italic>BRCA<\/jats:italic>+ men (<jats:italic>n<\/jats:italic>\u00a0=\u00a035) identified promoters and barriers to active coping response and intra\u2010familial communication of risk. Mapping results onto the TPB identified targets for tailoring person\u2010centered approaches for men addressing beliefs\/attitude, subjective norms, and perceived behavioral control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Men and women appear to have different coping responses to learning their<jats:italic>BRCA<\/jats:italic>status. Developing tailored (sex\u2010based), theory informed interventions may help promote intra\u2010familial communication of<jats:italic>BRCA<\/jats:italic>risk and support cascade screening.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.5831","type":"journal-article","created":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T17:53:31Z","timestamp":1632851611000},"page":"486-495","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Coping response and family communication of cancer risk in men harboring a<i>BRCA<\/i>mutation: A mixed methods study"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7023-6794","authenticated-orcid":false,"given":"Andrew A.","family":"Dwyer","sequence":"first","affiliation":[{"name":"William F. 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Evaluation, Statistics and Assessment Boston College Chestnut Hill Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,9,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.8430"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41436-019-0735-3"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10689-016-9889-1"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10897-011-9470-x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jgc4.1055"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10897-018-0214-z"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pec.2017.07.015"},{"issue":"2","key":"e_1_2_9_9_1","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1002\/pon.2106","article-title":"A follow\u2010up study on men tested for BRCA1\/BRCA2 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