{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:51:37Z","timestamp":1747151497525,"version":"3.40.5"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,12,5]],"date-time":"2021-12-05T00:00:00Z","timestamp":1638662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Cancer can be a life\u2010threatening stressor that may evoke pre\u2010existing post\u2010traumatic stress disorder (PTSD). We assessed change in 9\/11\u2010related PTSD symptoms following cancer diagnosis in a 9\/11\u2010exposed cohort, the World Trade Center Health Registry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We examined enrollees who had a first\u2010time post\u20109\/11 invasive cancer diagnosis and at least one pre\u2010 and two post\u2010diagnosis 9\/11\u2010related PTSD assessments from enrolment through 2015. PTSD symptoms were measured using 17\u2010item PTSD Checklist (PCL, range 17\u201085). Cancer was identified from New York State Cancer Registry and categorized as localized or advanced stage. We used piecewise spline linear mixed\u2010effects models to examine rate of change in PCL scores from pre\u2010 to post\u2010diagnosis periods, and whether the change differed by gender or stage, with time as fixed and random effects, adjusting for baseline age, race, and education.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>9\/11\u2010related PTSD symptoms were slightly increasing in the pre\u2010diagnosis period, while this trend reversed in the post\u2010diagnosis period (\u03b2: \u22120.38; 95% CI: \u22120.60, \u22120.15). This trend was driven by male rescue\/recovery workers (RRW), among whom significant decrease in rate of change in PCL scores was observed for those with advanced stage (slope change difference [95% CI]: \u22121.81 [\u22122.73, \u22120.90]). No significant difference in rate of change was observed among non\u2010RRW. Among females, PCL scores tended to decrease slightly, with no significant difference in rate of change between pre\u2010 and post\u2010diagnosis periods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We observed significant reduction in the rate of change in 9\/11\u2010related PTSD symptoms among male RRW. The underlying mechanism is unknown, necessitating future research.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.5855","type":"journal-article","created":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T04:06:19Z","timestamp":1638763579000},"page":"717-724","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Change in 9\/11\u2010related post\u2010traumatic stress symptoms following cancer diagnosis"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0144-1292","authenticated-orcid":false,"given":"Janette","family":"Yung","sequence":"first","affiliation":[{"name":"New York City Department of Health and Mental Hygiene World Trade Center Health Registry  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin","family":"Takemoto","sequence":"additional","affiliation":[{"name":"New York City Department of Health and Mental Hygiene World Trade Center Health Registry  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Cone","sequence":"additional","affiliation":[{"name":"New York City Department of Health and Mental Hygiene World Trade Center Health Registry  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiehui","family":"Li","sequence":"additional","affiliation":[{"name":"New York City Department of Health and Mental Hygiene World Trade Center Health Registry  New York New York 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