{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T15:15:17Z","timestamp":1774365317761,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,12,10]],"date-time":"2022-12-10T00:00:00Z","timestamp":1670630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006244","name":"Stichting Kinderen Kankervrij","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006244","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe health\u2010related quality of life (HRQoL), post\u2010traumatic stress and post\u2010traumatic growth of parents of long\u2010term survivors of childhood cancer (CCS) and study associated factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Parents of survivors of the Dutch Childhood Cancer Survivor Study LATER cohort below 30\u00a0years and diagnosed 1986\u20132001 were invited to complete the TNO\u2010AZL Questionnaire for Adult's HRQoL (e.g., sleep and aggressive emotions), Self\u2010Rating Scale for Post\u2010traumatic Stress Disorder, Post\u2010traumatic Growth Inventory, and Illness Cognition Questionnaire. HRQoL domain scores were compared to references using Mann\u2010Whitney U tests. Correlations between post\u2010traumatic stress, growth and HRQoL were evaluated. Medical characteristics of their child and illness cognitions were studied as associated factors of HRQOL, post\u2010traumatic stress and growth. <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05 was considered statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Parents (<jats:italic>n<\/jats:italic>\u00a0=\u00a0661 of <jats:italic>n<\/jats:italic>\u00a0=\u00a0448 survivors, 56% female, mean time since child's diagnosis: 21.3 [SD: 3.3] years) reported better HRQoL in social functioning and aggressive emotions than references (<jats:italic>r<\/jats:italic>\u00a0=\u00a0.08\u20130.17). Mothers additionally reported better HRQoL in pain, daily activities, sexuality, vitality, positive and depressive emotions (<jats:italic>r<\/jats:italic>\u00a0=\u00a0.07\u20130.14). Post\u2010traumatic stress was symptomatic in 3%, and associated with worse HRQoL (<jats:italic>r<\/jats:italic>\u00a0=\u00a0\u22120.27\u20130.48). Post\u2010traumatic growth was positively associated to post\u2010traumatic stress and better HRQoL (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.09\u20130.12). Cancer recurrence was associated to better HRQoL (<jats:italic>\u03b2<\/jats:italic>\u00a0=\u00a00.37\u20130.46). Acceptance illness cognitions were associated to better (<jats:italic>\u03b2<\/jats:italic>\u00a0=\u00a00.12\u20130.25), and helplessness to worse outcomes (<jats:italic>\u03b2<\/jats:italic>\u00a0=\u00a00.14\u20130.38).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>HRQoL of parents of young adult survivors of CCS is comparable to references or slightly better. Only a small proportion reports symptomatic post\u2010traumatic stress. Improving acceptance and reducing feelings of helplessness may provide treatment targets for parents with psychosocial problems.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.6069","type":"journal-article","created":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T10:00:39Z","timestamp":1669370439000},"page":"283-294","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Psychosocial functioning of parents of Dutch long\u2010term survivors of childhood cancer"],"prefix":"10.1002","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1690-5926","authenticated-orcid":false,"given":"Marloes","family":"van Gorp","sequence":"first","affiliation":[{"name":"Princess M\u00e1xima Center for Pediatric Oncology  Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mala M. H.","family":"Joosten","sequence":"additional","affiliation":[{"name":"Princess M\u00e1xima Center for Pediatric Oncology  Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Maas","sequence":"additional","affiliation":[{"name":"Princess M\u00e1xima Center for Pediatric Oncology  Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Babet L.","family":"Drenth","sequence":"additional","affiliation":[{"name":"Princess M\u00e1xima Center for Pediatric Oncology  Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alied","family":"van der Aa\u2013van Delden","sequence":"additional","affiliation":[{"name":"Princess M\u00e1xima Center for Pediatric Oncology  Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leontien C. M.","family":"Kremer","sequence":"additional","affiliation":[{"name":"Princess M\u00e1xima Center for Pediatric Oncology  Utrecht The Netherlands"},{"name":"Department of Pediatrics Amsterdam UMC University of Amsterdam  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eline","family":"van Dulmen\u2010den Broeder","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Amsterdam UMC location University of Amsterdam  Amsterdam The Netherlands"},{"name":"Amsterdam Reproduction and Development  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wim J. E.","family":"Tissing","sequence":"additional","affiliation":[{"name":"Princess M\u00e1xima Center for Pediatric Oncology  Utrecht The Netherlands"},{"name":"Department of pediatric oncology University of Groningen, University Medical Center Groningen  Groningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline J.","family":"Loonen","sequence":"additional","affiliation":[{"name":"Radboud University Medical Center  Nijmegen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena J. H.","family":"van der Pal","sequence":"additional","affiliation":[{"name":"Princess M\u00e1xima Center for Pediatric Oncology  Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrica C. H.","family":"de Vries","sequence":"additional","affiliation":[{"name":"Princess M\u00e1xima Center for Pediatric Oncology  Utrecht The Netherlands"},{"name":"Erasmus MC Sophia Children's Hospital Erasmus Medical Center  Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marry M.","family":"van den Heuvel\u2010Eibrink","sequence":"additional","affiliation":[{"name":"Princess M\u00e1xima Center for Pediatric Oncology  Utrecht The Netherlands"},{"name":"Erasmus MC Sophia Children's Hospital Erasmus Medical Center  Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9cile","family":"Ronckers","sequence":"additional","affiliation":[{"name":"Princess M\u00e1xima Center for Pediatric Oncology  Utrecht The Netherlands"},{"name":"Department of Health Services Research Carl v Ossietzky University of Oldenburg  Oldenburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorine","family":"Bresters","sequence":"additional","affiliation":[{"name":"Princess M\u00e1xima Center for Pediatric Oncology  Utrecht The Netherlands"},{"name":"Leiden University Medical Center  Leiden The Netherlands"},{"name":"Willem\u2010Alexander Children's Hospital  Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marloes","family":"Louwerens","sequence":"additional","affiliation":[{"name":"Leiden University Medical Center  Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian J. 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