{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:28:05Z","timestamp":1791840485918,"version":"4.3.4"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T00:00:00Z","timestamp":1672876800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100011851","name":"Kom op tegen Kanker","doi-asserted-by":"publisher","award":["G0D9621N"],"award-info":[{"award-number":["G0D9621N"]}],"id":[{"id":"10.13039\/501100011851","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["1126418N"],"award-info":[{"award-number":["1126418N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>A chronic feeling of fatigue occurs in up to 85% of childhood cancer survivors (CCS). This phenomenon has a detrimental effect on quality of life, reintegration in daily life activities and psychosocial functioning of the patient. Therefore, it is important to elucidate potential individual risk and protective factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>CCS who were treated in the University Hospital of Leuven, completed two annual questionnaires on cancer\u2010related distress (fear of cancer recurrence and post\u2010traumatic stress, resilience and fatigue). Associations between distress and fatigue levels were examined by performing cross\u2010lagged panel analyses. Resilience was included as a potential moderator. These models included all within\u2010time associations, stability paths, and cross\u2010lagged paths. Gender and time since diagnosis were included as covariates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 110 CCS participated in this study, aged 14\u201325\u00a0years (average time since diagnosis 12.2\u00a0years; 41.8% boys; diagnosed with leukemia\/lymphoma [49%], solid tumor [15%], brain tumor [16%] or other [20%]). Fear of cancer recurrence and post\u2010traumatic stress at baseline positively predicted fatigue 1\u00a0year later. Cross\u2010lagged panel analyses showed that resilience did not buffer the effect of fear of cancer recurrence on fatigue, in contrary to our expectations. Stability coefficients were high for all study variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study indicates associations between cancer\u2010related distress (fear of cancer recurrence and post\u2010traumatic stress), resilience and cancer\u2010related fatigue over time in CCS. Interventions to improve fatigue levels could be focusing on both tackling cancer\u2010related distress, while improving resilience levels as well.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pon.6084","type":"journal-article","created":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T05:58:50Z","timestamp":1672379930000},"page":"393-400","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Associations between cancer\u2010related distress and fatigue in\u00a0childhood cancer survivors: A longitudinal study"],"prefix":"10.1002","volume":"32","author":[{"given":"Deveny","family":"Vanrusselt","sequence":"first","affiliation":[{"name":"Department of Pediatric Hematology and Oncology University Hospitals Leuven  Leuven Belgium"},{"name":"Department of Oncology KU Leuven  Leuven 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