{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:52:15Z","timestamp":1786978335262,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T00:00:00Z","timestamp":1691539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>We aimed to test a model in which hope and spiritual well\u2010being acted as protective factors against anxiety and depressive symptoms in childhood cancer patients (CCPs). We hypothesized that hope and spiritual well\u2010being were mutually reinforcing factors that would both reduce anxiety and depressive symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using path analysis, the hypothetical model was tested on a cross\u2010sectional sample of 412 Chinese CCPs aged 8\u201317\u00a0years. Self\u2010reported measures were used to obtain data on participants' social and clinical characteristics, spiritual well\u2010being, hope, anxiety and depressive symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The hypothetical model was supported. Results suggested that sex, treatment type and diagnosis predicted spiritual well\u2010being; diagnosis and time since diagnosis predicted hope. Spiritual well\u2010being and hope were mutually predictive and mutually reinforcing, and were both negatively associated with anxiety and depressive symptoms. This model predicted 40% of the variance in spiritual well\u2010being, 37% in hope, 39% in depressive symptoms, and 28% in anxiety.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Spiritual well\u2010being and hope were mutually reinforcing and served as protective factors against anxiety and depressive symptoms. These support the value for integrating spiritual and hope elements in developing interventions for CCPs to improve their spiritual and psychological well\u2010being along the disease trajectory.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pon.6198","type":"journal-article","created":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T02:35:30Z","timestamp":1691634930000},"page":"1452-1460","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["The associations between spiritual well\u2010being, hope and psychological symptoms in Chinese childhood cancer patients: A path analysis"],"prefix":"10.1002","volume":"32","author":[{"given":"Qi","family":"Liu","sequence":"first","affiliation":[{"name":"School of Nursing Hong Kong Polytechnic University  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ka\u2010Yan","family":"Ho","sequence":"additional","affiliation":[{"name":"School 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