{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T05:39:36Z","timestamp":1780551576152,"version":"3.54.1"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T00:00:00Z","timestamp":1714608000000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>It is widely acknowledged that emotional states can influence skin conditions, yet limited research has delved into the impact of stress on skin cancer development. This retrospective study sought to expand the perspective on skin cancer risk factors by investigating the complex relationship between stressful life events and the incidence of skin cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The sample included 268 individuals followed\u2010up in a dermatological clinic, in three groups: Patients who had previously been diagnosed with cutaneous melanoma and are currently in remission (32%), those who had been diagnosed with non\u2010melanoma skin cancer (30%), and a control group who are at risk for skin cancer (38%). Participants filled in questionnaires regarding childhood and adulthood life events, and loss and gain of resources following their subjectively most stressful event in adulthood. Multinomial logistic regression was used to examine the associations of life events with skin cancer occurrence, and mediating and moderating effects of resource loss\/gain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Adverse childhood experiences were associated with melanoma occurrence, with the melanoma group reporting significantly more such experiences compared to the control group (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001). Resource loss from subjectively significant stressful life events in adulthood partially mediated the association between adverse childhood experiences and melanoma incidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The findings suggest that there may be intricate connections between stress, life events, adaptation to change, and skin cancer, which future research may further unravel. This study underscores the need for a more comprehensive approach to stress management, coping strategies development, and skin cancer prevention in healthcare settings.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.6343","type":"journal-article","created":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T01:08:20Z","timestamp":1714698500000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Stressful life events and the occurrence of skin cancer"],"prefix":"10.1002","volume":"33","author":[{"given":"Noa","family":"Shidlo","sequence":"first","affiliation":[{"name":"Bob Shapell School of Social Work Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aneta","family":"Lazarov","sequence":"additional","affiliation":[{"name":"Clinic for Early Detection of Skin Cancer  Herzliya Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5110-8212","authenticated-orcid":false,"given":"Yael","family":"Benyamini","sequence":"additional","affiliation":[{"name":"Bob Shapell School of Social Work Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5,2]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010psych\u2010010418\u2010102857"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0149\u20107634(03)00005\u20108"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/s2468\u20102667(17)30118\u20104"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m3048"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.14.1685"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2021.105088"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015\u20104268l"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncponc1134"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/cdr.cdr_116_20"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2023.111350"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/cej.0000000000000567"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/cmr.0000000000000380"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2011.1535"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555\u20102045"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403\u2010013\u20101373\u20102"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dji401"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1037\/0003\u2010066x.44.3.513"},{"key":"e_1_2_11_19_1","first-page":"127","volume-title":"The Oxford handbook of stress, health, and coping","author":"Hobfoll SE","year":"2011"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.3758\/bf03193146"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14861"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2007.46"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/1077559516679513"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939\u20100025.2012.01149.x"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00127\u2010009\u20100020\u2010x"},{"key":"e_1_2_11_26_1","first-page":"125","volume-title":"The Meaning and Measurement of Support","author":"Hobfoll SE","year":"1992"},{"key":"e_1_2_11_27_1","volume-title":"Key Resources and Engagement Among Professional Athletes [Unpublished Master\u2019s Thesis]","author":"Nahum O","year":"2019"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1159\/000056237"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403\u2010013\u20101373\u20102"},{"key":"e_1_2_11_30_1","first-page":"1","volume-title":"ABC of Skin Cancer. 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