{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:05:58Z","timestamp":1790687158962,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T00:00:00Z","timestamp":1730332800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Over half of new cancer diagnoses occur in patients aged 65 or older, with up to 40% experiencing anxiety. The American Society of Clinical Oncology recommends using the Generalized Anxiety Disorder Scale (GAD\u20107) for anxiety screening, but the GAD\u20107 psychometric properties in this population are unknown. This study examined the GAD\u20107's reliability, validity, and item parameters, comparing its utility with the GAD\u20102 in older adults with cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional secondary analysis of a nationwide multi\u2010site two\u2010arm cluster randomized trial in older adults (\u2265\u00a070)\u00a0with advanced cancer. The GAD\u20107 was administered at baseline. Properties were evaluated with Cronbach's <jats:italic>\u03b1<\/jats:italic>, Pearson correlation coefficients, and a 2\u2010parameter logistic model. Logistic regression models compared the GAD\u20102 and GAD\u20107.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The sample included 718 participants (Mean age\u00a0=\u00a077, SD\u00a0=\u00a05) with mild anxiety (<jats:italic>M<\/jats:italic>\u00a0=\u00a03.74, SD\u00a0=\u00a04.74). Internal consistency was strong (Cronbach's alpha\u00a0=\u00a00.89) and item\u2010total correlations ranged 0.53 to 0.78. Item 2 (Not being able to stop or control worrying) was the most discriminating and item 5 (Being so restless that it is hard to sit still) was least discriminating. Area Under the Curve (AUC) analyses demonstrated the GAD\u20102 had a 0.93\u20130.96 AUC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Establishing the psychometric properties of anxiety screening measures is crucial in the older adults with cancer to maximize referral efficiency and accuracy. This study indicates that the GAD\u20107 is reliable and valid for older adults with cancer. Analyses suggest the GAD\u20102 may be as sufficient as the GAD\u20107 in identifying anxiety in older adults with cancer, thereby reducing assessment burden.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.70012","type":"journal-article","created":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T23:59:07Z","timestamp":1730419147000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Psychometric Properties of the Generalized Anxiety Disorder Scale (GAD\u20107) in Older Adults With Advanced Cancer"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1093-7676","authenticated-orcid":false,"given":"Rebecca M.","family":"Saracino","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Behavioral Science Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee A.","family":"Kehoe","sequence":"additional","affiliation":[{"name":"James P. Wilmot Cancer Institute University of Rochester School of Medicine and Dentistry  Rochester New York USA"},{"name":"Division of Supportive Care in Cancer Department of Surgery University of Rochester School of Medicine and Dentistry  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Sohn","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Computational Biology University of Rochester School of Medicine and Dentistry  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Computational Biology University of Rochester School of Medicine and Dentistry  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Supriya","family":"Mohile","sequence":"additional","affiliation":[{"name":"James P. Wilmot Cancer Institute University of Rochester School of Medicine and Dentistry  Rochester New York USA"},{"name":"Division of Hematology\/Oncology Department of Medicine University of Rochester School of Medicine and Dentistry  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Wells","sequence":"additional","affiliation":[{"name":"James P. Wilmot Cancer Institute University of Rochester School of Medicine and Dentistry  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Mustian","sequence":"additional","affiliation":[{"name":"James P. Wilmot Cancer Institute University of Rochester School of Medicine and Dentistry  Rochester New York USA"},{"name":"Division of Supportive Care in Cancer Department of Surgery University of Rochester School of Medicine and Dentistry  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Morrow","sequence":"additional","affiliation":[{"name":"James P. Wilmot Cancer Institute University of Rochester School of Medicine and Dentistry  Rochester New York USA"},{"name":"Division of Supportive Care in Cancer Department of Surgery University of Rochester School of Medicine and Dentistry  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Bradley","sequence":"additional","affiliation":[{"name":"Northwell Health NCORP Northwell RJ Zuckerberg Cancer Center  New Hyde Park New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9185-0606","authenticated-orcid":false,"given":"Adedayo","family":"Onitilo","sequence":"additional","affiliation":[{"name":"Wisconsin NCORP Marshfield Clinic  Marshfield Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Giguere","sequence":"additional","affiliation":[{"name":"NCORP of the Carolinas Prisma Health  Greenville South Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2018-1860","authenticated-orcid":false,"given":"Kelly M.","family":"McConnell","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Science Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2666\u20107568(21)00179\u20103"},{"key":"e_1_2_9_3_1","volume-title":"Surveillance Research Program","author":"SEER*Explorer: An Interactive Website for SEER Cancer Statistics [Internet]","year":"2023"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjspcare\u20102017\u2010001388"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055\u20109965.epi\u201016\u20100133"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2014.09.008"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4404"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgo.2017.01.003"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2016.12.007"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.14301"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2016\u20100033"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010020\u201005297\u20100"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.23.00293"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.10.1092"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596.dsm05"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.50.5.440"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010008\u20100529\u20107"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2008.0158"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2011.05.003"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0885\u20103924(00)00126\u20103"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s005200000221"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1188\/10.onf.469\u2010475"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2008.03.005"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097\u20104679(198901)45:1<20::AID\u2010JCLP2270450103>3.0.CO;2\u2010Z"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2002.07.101"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3714"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4681"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jagp.2013.01.076"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(21)01789\u2010X"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u20105415.2005.53461.x"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022\u20103956(82)90033\u20104"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/nur.4770140211"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1080\/10705519909540118"},{"issue":"6","key":"e_1_2_9_34_1","first-page":"1","article-title":"A Multidimensional Item Response Theory Package for the R Environment","volume":"48","author":"Mirt C. 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