{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:28:01Z","timestamp":1791419281418,"version":"4.3.3"},"reference-count":35,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Psychosocial risk factors (PSRFs) have emerged as important nontraditional risk factors for poor medical outcomes but have not been well\u2010studied in the field of hematopoietic stem cell transplantation (HSCT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>In this study, we retrospectively examined in\u2010hospital and short\u2010term outcomes in patients with PSRFs who underwent HSCT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We used the National Readmission Database (NRD) to identify patients who underwent HSCT between 2011 and 2020. Patients were stratified based on the presence of either 0 or \u2265 1 PSRFs, which included factors such as mental illness, substance abuse, cognitive problems, a low income level, and an uninsured status. Patients were also classified into allogeneic\u2010HSCT (allo\u2010HSCT) and autologous\u2010HSCT (auto\u2010HSCT) groups. Our primary endpoints were in\u2010hospital and short\u2010term outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In this nationally representative cohort, 90,747 patients underwent auto\u2010HSCT, while 26,600 patients underwent allo\u2010HSCT. In the auto\u2010HSCT group, individuals with PSRFs exhibited notably higher in\u2010hospital mortality (2.4% vs. 2.8%; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) and 30\u2010day all\u2010cause readmission rates (14.4% vs. 17.8%; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) compared to those without PSRFs. Similarly, within the allo\u2010HSCT group, patients with PSRFs had significantly higher in\u2010hospital mortality (5.4% vs. 6.4%; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) and 30\u2010day all\u2010cause readmission rates (27.3% vs. 31.2%; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) compared to those without PSRFs. After adjusting for risk factors, the presence of PSRFs emerged as a substantial predictor for heightened 30\u2010day readmission in allo\u2010HSCT and auto\u2010HSCT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The presence of PSRFs is correlated with poorer in\u2010hospital and short\u2010term outcomes after both allo\u2010HSCT and auto\u2010HSCT, with a more pronounced effect observed in allo\u2010HSCT. This research underscores the significance of pinpointing high\u2010risk patients and implies support for merging PSRFs after HSCT is beneficial.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.70032","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:39:27Z","timestamp":1732063167000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Psychological Risk Factors on Hematopoietic Stem Cell Transplantation Patients: Insights From National Readmission Database Analysis"],"prefix":"10.1002","volume":"33","author":[{"given":"Qi","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Hematology Tengzhou Central People's Hospital  Tengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuyan","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Hematology Tengzhou Central People's Hospital  Tengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Hematology Tengzhou Central People's Hospital  Tengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongjing","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Hematology Tengzhou Central People's Hospital  Tengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Hematology Tengzhou Central People's Hospital  Tengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Hematology Tengzhou Central People's Hospital  Tengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Hematology Tengzhou Central People's Hospital  Tengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Hematology Tengzhou Central People's Hospital  Tengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Hematology Tengzhou Central People's Hospital  Tengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xunxun","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Hematology Tengzhou Central People's Hospital  Tengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Hematology Tengzhou Central People's Hospital  Tengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Cardiology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1470\u20102045(14)70115\u20109"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(05)66665\u20102"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(03)14190\u20106"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890\u2010200009150\u201000001"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2023.08.028"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2022.08.014"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.12214"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13447"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11897\u2010019\u201000443\u20100"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2019.06.019"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41409\u2010019\u20100455\u2010y"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41409\u2010018\u20100371\u20106"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0022\u20103999(02)00413\u20100"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq433"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11899\u2010016\u20100328\u2010z"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010014\u20102264\u20106"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440\u20101819.2003.01084.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29877"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2014.139"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29818"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2022007548"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2016.06.007"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psym.2019.01.005"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2012.09.013"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.3109\/00952999709040948"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.45.5.378"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41409\u2010023\u201001921\u20109"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2012.03.025"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1705419"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2020.0021"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.160.14.2101"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30546"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3462"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2009.166"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2013.228"}],"container-title":["Psycho-Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pon.70032","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T15:26:17Z","timestamp":1755962777000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pon.70032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":35,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1002\/pon.70032"],"URL":"https:\/\/doi.org\/10.1002\/pon.70032","archive":["Portico"],"relation":{},"ISSN":["1057-9249","1099-1611"],"issn-type":[{"value":"1057-9249","type":"print"},{"value":"1099-1611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"2024-01-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70032"}}