{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T18:25:41Z","timestamp":1759775141458,"version":"3.41.2"},"reference-count":40,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T00:00:00Z","timestamp":1734566400000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The diagnosis of a mood\u2010related psychiatric disorder (MRPD) among patients with cancer has been associated with decreased quality of life and lower cancer survival. This study aimed to understand the risk of a new MRPD after cancer diagnosis by individual risk behaviors, with a specific focus on tobacco use and the presence of a human papillomavirus (HPV)\u2010associated cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Single\u2010center retrospective cohort study of 11,712 patients diagnosed with cancer between 2009 and 2020. We identified predictors of a new MRPD after cancer diagnosis using a time\u2010to\u2010event analysis and Cox proportional hazards model including demographics, disease characteristics, and tobacco use and HPV\u2010associated tumors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Univariate analyses revealed lower hazard ratios (HRs) of a new MRPD among individuals that identified as Asian\/Pacific Islanders and among the older age groups (&gt;\u00a051\u00a0years). Univariate analyses additionally demonstrated higher HRs of MRPD among females; sexual minorities; former and current smokers; individuals with HPV\u2010associated cancers; and individuals diagnosed at later stages. These relationships were observed in the multivariate model when adjusting for covariates. Shorter time\u2010to\u2010MRPD was observed when stratifying by individual behavioral risk factors, with active smokers and individuals with an HPV\u2010associated cancer being at the highest risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Individual behavioral risk factors increase risk of new MRPD after being diagnosed with cancer. These findings build on past studies by linking tobacco use and HPV\u2010associated cancers with MRPD risk in oncology and can be used to identify patients at risk of developing new MRPDs post\u2010cancer diagnosis and engaging them in treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.70046","type":"journal-article","created":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T03:32:37Z","timestamp":1734665557000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Predictive Value of Individual Behavioral Risk Factors for New Mood\u2010Related Psychiatric Disorder After Diagnosis of Cancer"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2442-576X","authenticated-orcid":false,"given":"Seiichi","family":"Villalona","sequence":"first","affiliation":[{"name":"Department of Medicine University of Pennsylvania Perelman School of Medicine  Philadelphia Pennsylvania USA"},{"name":"Department of Internal Medicine Hospital of the University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Chavez","family":"Perez","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Pennsylvania Perelman School of Medicine  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. Paul","family":"Wileyto","sequence":"additional","affiliation":[{"name":"Biostatistics University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Takvorian","sequence":"additional","affiliation":[{"name":"Division of Hematology &amp; Oncology Department of Medicine University of Pennsylvania Perelman School of Medicine  Philadelphia Pennsylvania USA"},{"name":"Abramson Cancer Center University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Gabriel","sequence":"additional","affiliation":[{"name":"Abramson Cancer Center University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abigail","family":"Doucette","sequence":"additional","affiliation":[{"name":"Department of Biostatistics University of Pennsylvania Perelman School of Medicine  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Blumenthal","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Pennsylvania Perelman School of Medicine  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4089-856X","authenticated-orcid":false,"given":"Robert","family":"Schnoll","sequence":"additional","affiliation":[{"name":"Abramson Cancer Center University of Pennsylvania  Philadelphia Pennsylvania USA"},{"name":"Department of Psychiatry University of Pennsylvania Perelman School of Medicine  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,12,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1470\u20102045(11)70002\u2010x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k1415"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/s2215\u20100366(14)70313\u2010x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/s0033291709992285"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24561"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380\u2010019\u20100595\u2010x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0006\u20103223(03)00566\u20103"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2016.0483"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5033"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2000.18.4.893"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1017\/S147895152200116X"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6526a1"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2007.07.013"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2009.037028"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5803"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2016.34.26_suppl.87"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.12999"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.21037\/tcr.2019.11.04"},{"volume-title":"HPV\u2010Related Shame, Stigma, Depression and Anxiety in Women with Cervical Cancer [Doctoral]","year":"2018","author":"Caswell A.","key":"e_1_2_10_20_1"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soc.2016.07.014"},{"issue":"4","key":"e_1_2_10_22_1","first-page":"252","article-title":"Anal Cancer Is on the Rise; It's a Shame","volume":"45","author":"Leppard S.","year":"2016","journal-title":"Australian Family Physician"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2005.016436"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1017\/s0022215117001098"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.31800"},{"volume-title":"Definitions of Risk Factor\u2010Associated Cancers. 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