{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:31:46Z","timestamp":1787725906157,"version":"build-2784847793"},"reference-count":68,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T00:00:00Z","timestamp":1736726400000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004830","name":"State of Connecticut Office of Policy and Management","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004830","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Adolescents and young adults (AYA) with cancer experience long\u2010term consequences into survivorship that impact quality of life, including mental health symptoms, substance use, and persistent pain. Given the elevated rates of pain, AYA cancer survivors are at increased risk for opioid pain medication (OPM) exposure, increasing risk for opioid\u2010related negative consequences, particularly for those with mental health symptoms. Minimal research has documented that a considerable proportion of AYAs with cancer receive OPM that continues into survivorship, yet the lack of consensus on the definition of problematic opioid use coupled with the high clinical need for OPM makes it particularly challenging to understand the impact of OPM use in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>Therefore, the current study examined differences in opioid pain medication use, use behaviors, and motives between AYA cancer survivors and non\u2010cancer controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using the National Survey on Drug Use and Health, we tested the impact of OPM use behaviors and motives on depressive symptoms and mental healthcare utilization variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Results show that, compared to non\u2010cancer controls, AYA cancer survivors evince higher rates of opioid use, behaviors, and pain relief motives. Within the cancer survivor group only, there were differential patterns of associations between OPM behaviors, motives, depressive symptoms, and mental healthcare utilization, with using opioid pain medication for emotion coping\/to get high showed the largest effect sizes with outcome variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results highlight the importance of moving beyond use itself and examining how and why AYAs with cancer are using opioids to understand potential negative consequences.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.70082","type":"journal-article","created":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T15:38:27Z","timestamp":1736782707000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Mental Health Consequences of Opioid Pain Medication Use Behaviors and Motives Among Adolescents and Young Adults With Cancer: Results From a National Survey"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0755-8659","authenticated-orcid":false,"given":"Andrew H.","family":"Rogers","sequence":"first","affiliation":[{"name":"Division of Behavioral Medicine Department of Medicine University at Buffalo State University of New York  Buffalo New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Pielech","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Human Behavior Warren Alpert Medical School of Brown University  Providence Rhode Island USA"},{"name":"Center for Alcohol and Addiction Studies Brown University School of Public Health  Providence Rhode Island USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler G.","family":"Ketterl","sequence":"additional","affiliation":[{"name":"Ben Towne Center for Childhood Cancer Research Seattle Children's Hospital  Seattle Washington USA"},{"name":"Department of Pediatrics Division of Pediatric Hematology Oncology and Bone Marrow Transplant University of Washington School of Medicine  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tonya M.","family":"Palermo","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine University of Washington  Seattle Washington USA"},{"name":"Seattle Children's Research Institute Seattle Children's Hospital  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,13]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"N. C.Institute Adolescents and Young Adults with Cancer (2024) https:\/\/www.cancer.gov\/types\/aya."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21637"},{"key":"e_1_2_10_4_1","first-page":"235","volume-title":"Overview of Adolescent and Young Adult Oncology","author":"Coccia P. F.","year":"2019"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13194847"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1089\/jayao.2022.0136"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1200\/jco.23.01615"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/ncc.0000000000000972"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29866"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.6001"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4730"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.27486"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.33634"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3958"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5378"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1188\/15.cjon.19\u201006ap"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21453"},{"key":"e_1_2_10_18_1","first-page":"1428","volume-title":"Cancer Pain Management","author":"Smith T. J.","year":"2015"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp2312084"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2020.38.29_suppl.136"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.34238"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.19.2087"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2004.06.007"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpt.13114"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2019\u20100540"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.34384"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.33963"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010020\u201005980\u20102"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/2167702620978614"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1037\/1040\u20103590.6.2.117"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033\u2010295X.111.1.33"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2017.10.010"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.4088\/jcp.20m13302"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751\u20107893.2008.00076.x"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.15288\/jsad.2011.72.106"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0031065"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2021.639578"},{"key":"e_1_2_10_38_1","unstructured":"Institute NC National Cancer Institute Dictionary of Cancer Terms. (2024) https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer\u2010terms\/def\/survivor."},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1037\/10518\u2010009"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12955\u2010018\u20100858\u20102"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000083169.58671.96"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1214\/aos\/1176350273"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1981.10477633"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/biom.12297"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.15396"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2021.108588"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2008.01.027"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1177\/21925682211070823"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/bf03405775"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1080\/00221325.2022.2130025"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v009.i08"},{"key":"e_1_2_10_53_1","volume-title":"National Survey on Drug Use and Health: Quality Assessment of the 2002 to 2013 NSDUH Public Use Files","author":"Substance A, Mental Health Services A. CBHSQ Methodology Report","year":"2016"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654\u2010016\u20100149\u20103"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745\u20106924.2008.00079.x"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1089\/jayao.2022.0130"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.35946\/arcr.v41.1.08"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2011.11.014"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2017.07.029"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2021.107173"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1080\/10826084.2016.1201510"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0304\u20103959(99)00006\u20108"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12094\u2010019\u201002268\u20108"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016\u20100258"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1037\/amp0000655"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010clinpsy\u2010050718\u2010095440"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1037\/amp0000678"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2021.10.015"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1200\/jco.20.03609"}],"container-title":["Psycho-Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pon.70082","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T05:50:34Z","timestamp":1738129834000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pon.70082"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":68,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1002\/pon.70082"],"URL":"https:\/\/doi.org\/10.1002\/pon.70082","archive":["Portico"],"relation":{},"ISSN":["1057-9249","1099-1611"],"issn-type":[{"value":"1057-9249","type":"print"},{"value":"1099-1611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-08-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70082"}}