{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T19:42:34Z","timestamp":1781725354497,"version":"3.54.5"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T00:00:00Z","timestamp":1752796800000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>A large proportion of prostate cancer (PCa) patients also report being anxious, which can impede their recovery and adversely influence their personal relationships.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>In order to better understand the <jats:italic>relationships between symptoms of anxiety<\/jats:italic> in these men, with a view towards more informed treatments for anxiety, the network structure of the symptomatology for Generalised Anxiety Disorder (GAD) was examined in this study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 425 PCa patients completed the GAD\u20107 and an extended version of that inventory (the GAD\u201010). Data were analysed via Network Analysis, Pearson correlation coefficients, and ANOVA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Network analysis and multidimensional scaling indicated that being unable to control worry was the most central symptom for these men, and that several sets of GAD symptoms were closely associated with each other. These included worrying, inability to relax, and restlessness. Other anxiety symptoms such as sleeping problems, difficulty concentrating, and feeling tyred were less well\u2010related with the remainder of the network. Implications for clinical practice were derived from the relationships between individual anxiety symptoms and the overall anxiety network by examining node predictability, and focused upon helping these men to \u2018switch off\u2019 from their worry by engaging in mutually\u2010incompatible behaviours.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The use of total anxiety inventory scores fails to identify the underlying network structure of anxiety in PCa patients. By finding the central GAD symptom of being unable to control their worry, more individually\u2010focussed anti\u2010anxiety treatments might be developed and offered to these men.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pon.70237","type":"journal-article","created":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T03:44:53Z","timestamp":1752896693000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Network Analysis of Anxiety in Prostate Cancer Patients"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7922-4848","authenticated-orcid":false,"given":"Christopher F.","family":"Sharpley","sequence":"first","affiliation":[{"name":"Brain\u2010Behaviour Research Group University of New England  Armidale Australia"},{"name":"School of Science &amp; Technology University of New England  Armidale Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca J.","family":"Williams","sequence":"additional","affiliation":[{"name":"Brain\u2010Behaviour Research Group University of New England  Armidale Australia"},{"name":"Faculty of Health Charles Darwin University  Darwin Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicki","family":"Bitsika","sequence":"additional","affiliation":[{"name":"Brain\u2010Behaviour Research Group University of New England  Armidale Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne M.","family":"Arnold","sequence":"additional","affiliation":[{"name":"Brain\u2010Behaviour Research Group University of New England  Armidale Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5494-8751","authenticated-orcid":false,"given":"David R. H.","family":"Christie","sequence":"additional","affiliation":[{"name":"Brain\u2010Behaviour Research Group University of New England  Armidale Australia"},{"name":"GenesisCare John Flynn Hospital  Tugun Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,18]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41391\u2010020\u201000286\u20100"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40359\u2010023\u201001159\u20106"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.3069"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010022\u201006876\u2010z"},{"key":"e_1_2_9_6_1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders 5th Ed Text Revision","author":"APA","year":"2022"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1623"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2021.719490"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43586\u2010021\u201000055\u2010w"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.10.1092"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1037\/met0000471"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3758\/s13428\u2010021\u201001587\u20105"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/16506073.2018.1560358"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.22744"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000512843"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u2010981\u201032\u20109705\u20100_17"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2020.0940"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/ju.0000000000002334"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41391\u2010021\u201000342\u20103"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20884"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.4324\/9781315724539-2"}],"container-title":["Psycho-Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pon.70237","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T14:36:28Z","timestamp":1754490988000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pon.70237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":20,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/pon.70237"],"URL":"https:\/\/doi.org\/10.1002\/pon.70237","archive":["Portico"],"relation":{},"ISSN":["1057-9249","1099-1611"],"issn-type":[{"value":"1057-9249","type":"print"},{"value":"1099-1611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"2024-08-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70237"}}