{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:26:27Z","timestamp":1790353587931,"version":"4.1.0"},"reference-count":62,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T00:00:00Z","timestamp":1758240000000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This review explores the impact of cancer on adolescents' and young adults' (AYAs) romantic and sexual relationships, examining both challenges and opportunities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Qualitative studies on AYAs with cancer and\/or their partners were searched based on a sub\u2010set of studies identified in a previous literature review within the EU Horizon STRONG\u2010AYA project, and supplemented with an additional search on romantic\/sexual relationships. Articles were screened, reviewed in Rayyan and data extracted using a structured framework. Study quality was appraised, and findings were synthesised thematically.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty studies were included. Findings revealed how cancer altered AYAs' sense of self, affecting the navigation of romantic relationships and sexual intimacy across four themes: (1)\n                      <jats:italic>Romantic relationship development\u2010connection, isolation and changing priorities<\/jats:italic>\n                      : Disrupted romantic trajectories and fears of being undesirable hindered relationship formation, though some re\u2010evaluated priorities, deepening emotional connections, (2)\n                      <jats:italic>The disclosure dance: Finding the right time and way<\/jats:italic>\n                      : AYAs struggled with when and how to disclose their diagnosis, with anxiety about burdening partners or altering dynamics. Open and honest communication fostered intimacy, (3)\n                      <jats:italic>Body image, sexuality, intimacy, and fertility<\/jats:italic>\n                      : Challenges in these areas impacted self\u2010worth, but also led to sexual empowerment and adapted intimacy, (4)\n                      <jats:italic>Partnerships and social support during cancer<\/jats:italic>\n                      : Unsupportive partners heightened isolation, while supportive partners reinforced self\u2010worth. Many AYAs experienced growth, resilience and a deeper understanding of themselves\/their relationships.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Results may inform age\u2010appropriate interventions to adequately address the unique challenges AYAs with cancer face in navigating romantic relationships and sexual intimacy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pon.70285","type":"journal-article","created":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T02:45:40Z","timestamp":1758336340000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Navigating Romantic Relationships and Sexual Intimacy: Challenges and Opportunities for Adolescents and Young Adults With Cancer \u2010 A Literature Review of Qualitative Studies"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1398-9105","authenticated-orcid":false,"given":"Nicole","family":"Colla\u00e7o","sequence":"first","affiliation":[{"name":"School of Health Sciences University of Southampton  Southampton England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8406-863X","authenticated-orcid":false,"given":"C\u00e9line","family":"Bolliger","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences and Medicine University of Lucerne  Lucerne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Cairns","sequence":"additional","affiliation":[{"name":"School of Health Sciences University of Southampton  Southampton England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Sodergren","sequence":"additional","affiliation":[{"name":"School of Health Sciences University of Southampton  Southampton England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Husson","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Netherlands Cancer Institute  Amsterdam the Netherlands"},{"name":"Department of Public Health Erasmus MC Cancer Institute Erasmus University Medical Center  Rotterdam the Netherlands"},{"name":"Department of Surgical Oncology Erasmus MC Cancer Institute Erasmus University Medical Center  Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Winette T. A.","family":"van der Graaf","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Netherlands Cancer Institute  Amsterdam the Netherlands"},{"name":"Department of Medical Oncology Erasmus MC Cancer Institute Erasmus University Medical Center  Erasmus the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Rothmund\u2010Grenier","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Psychotherapy, Psychosomatics, and Medical Psychology University Clinic of Psychiatry II Innsbruck Medical University  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milou J. P.","family":"Reuvers","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Netherlands Cancer Institute  Amsterdam the Netherlands"},{"name":"Department of Medical Oncology Erasmus MC Cancer Institute Erasmus University Medical Center  Erasmus the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gudrun E.","family":"Rohde","sequence":"additional","affiliation":[{"name":"Department of Health and Nursing Science Faculty of Health and Sport Sciences University in Agder  Kristiansand Norway"},{"name":"Department of Clinical Research Sorlandet Hospital  Sorlandet Norway"},{"name":"Marie Curie Palliative Care Research Department Division of Psychiatry University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8790-1247","authenticated-orcid":false,"given":"Anna L.","family":"Hurley\u2010Wallace","sequence":"additional","affiliation":[{"name":"School of Health Sciences University of Southampton  Southampton England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Angoumis","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Netherlands Cancer Institute  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2556-4553","authenticated-orcid":false,"given":"Emily I.","family":"Holthuis","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Netherlands Cancer Institute  Amsterdam the Netherlands"},{"name":"Department of Medical Oncology Erasmus MC Cancer Institute Erasmus University Medical Center  Erasmus the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina H.","family":"Lankhorst","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Netherlands Cancer Institute  Amsterdam the Netherlands"},{"name":"Department of Medical Oncology Erasmus MC Cancer Institute Erasmus University Medical Center  Erasmus the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1821-3760","authenticated-orcid":false,"given":"Catarina S.","family":"Padilla","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Netherlands Cancer Institute  Amsterdam the Netherlands"},{"name":"Department of Public Health Erasmus MC Cancer Institute Erasmus University Medical Center  Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Hanebaum","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Netherlands Cancer Institute  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Connor J.","family":"Tyler","sequence":"additional","affiliation":[{"name":"School of Health Sciences University of Southampton  Southampton England"},{"name":"Bioscience, Syngenta Crop Protection  Syngenta England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine J.","family":"Hunt","sequence":"additional","affiliation":[{"name":"School of Health Sciences University of Southampton  Southampton England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsty","family":"Way","sequence":"additional","affiliation":[{"name":"School of Health Sciences University of Southampton  Southampton England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Wagland","sequence":"additional","affiliation":[{"name":"School of Health Sciences University of Southampton  Southampton England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Cartledge","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Academic Geriatric Medicine University of Southampton  Southampton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thom","family":"Legendal","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Netherlands Cancer Institute  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvie H. 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