{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T17:42:06Z","timestamp":1776015726309,"version":"3.50.1"},"reference-count":39,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>In the context of cancer, pain demands interpretation. Our research has found that fear of cancer recurrence (FCR) is associated with the tendency to interpret ambiguous information as health\u2010related. We aimed to determine whether we could modify these interpretation biases to improve FCR, and pain outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a double\u2010blind randomized controlled trial comparing two fully automated Cognitive Bias Modification for Interpretation (CBM\u2010I) programs to a matched sham. We randomized 174 people with breast or ovarian cancer to one of three groups (pain\u2010related CBM, cancer\u2010specific CBM or sham). Participants completed four training sessions, and outcomes were assessed before and after intervention and 2\u00a0weeks later. We nominated co\u2010primary outcomes as FCR and fear of progression (FoP) so that measures were suited to those with and without active disease and measured pain outcomes and other secondary psychosocial outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We analyzed data using mixed\u2010model linear regression and intention\u2010to\u2010treat. Results indicated that both the cancer\u2010specific and pain\u2010related training groups showed significant improvements in FCR (\n                      <jats:italic>F<\/jats:italic>\n                      <jats:sub>(2,440)<\/jats:sub>\n                      \u00a0=\u00a017.19,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.0005) and FoP (\n                      <jats:italic>F<\/jats:italic>\n                      <jats:sub>(2,440)<\/jats:sub>\n                      \u00a0=\u00a015.03,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.0005) over time compared to sham. Both versions of CBM were associated with benefits in pain intensity (\n                      <jats:italic>F<\/jats:italic>\n                      <jats:sub>(2,440)<\/jats:sub>\n                      \u00a0=\u00a06.14,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.0005) and pain interference (\n                      <jats:italic>F<\/jats:italic>\n                      <jats:sub>(2,440)<\/jats:sub>\n                      \u00a0=\u00a05.223,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.001) compared to sham. No other secondary outcomes improved.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CBM for interpretation is an efficacious treatment for FCR, FoP and pain outcomes in ovarian and breast cancer. This intervention was delivered wholly online, had high completion rates (80%) and therefore is highly scalable. CBM\u2010I could be part of a stepped care model to meet the large unmet need for people who are living with and beyond cancer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pon.70338","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T04:40:43Z","timestamp":1764304843000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Double\u2010Blind Randomized Sham\u2010Controlled Trial of Two Online Cognitive Bias Modification Interventions for Fear of Cancer Recurrence in People With Breast or Ovarian Cancer"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9308-5717","authenticated-orcid":false,"given":"Poorva","family":"Pradhan","sequence":"first","affiliation":[{"name":"School of Psychology The University of Sydney  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8790-6272","authenticated-orcid":false,"given":"Louise","family":"Sharpe","sequence":"additional","affiliation":[{"name":"School of Psychology The University of Sydney  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayley","family":"Russell","sequence":"additional","affiliation":[{"name":"Ovarian Cancer Australia Queen Victoria Women's Centre  Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4962-0847","authenticated-orcid":false,"given":"Jemma","family":"Todd","sequence":"additional","affiliation":[{"name":"School of Psychology The University of Sydney  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy G.","family":"Lichtenthal","sequence":"additional","affiliation":[{"name":"Sylvester Comprehensive Cancer Center University of Miami Health System  Miami Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Courtney","family":"Beard","sequence":"additional","affiliation":[{"name":"Department of Psychiatry McLean Hospital Harvard Medical School  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phyllis","family":"Butow","sequence":"additional","affiliation":[{"name":"School of Psychology The University of Sydney  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5921"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.4143\/crt.2021.835"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3022"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5673"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5551"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764\u2010013\u20100272\u2010z"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000214"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000872"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5748"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1037\/hea0001217"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4620"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215\u20100366(20)30130\u20109"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2019.10.005"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000002784"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30478"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.19.00572"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5233"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2017.73.1257"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5218"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764\u2010022\u201001233\u20109"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010008\u20100444\u2010y"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2005.02.007"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10608\u2010009\u20109235\u20100"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5944"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1037\/1076\u20108998.3.4.356"},{"issue":"2","key":"e_1_2_10_28_1","first-page":"129","article-title":"Pain Assessment: Global Use of the Brief Pain Inventory","volume":"23","author":"Cleeland C. 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