{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:25:11Z","timestamp":1772987111363,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:00:00Z","timestamp":1769126400000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n \n High\u2010risk mothers undergoing\n BRCA<\/jats:italic>\n testing must decide whether, when, and how to disclose hereditary cancer risk information to their adolescent and young adult (AYA) children.\n <\/jats:p>\n <\/jats:sec>\n \n Aims<\/jats:title>\n This study explored maternal preferences\/values and cognitive\u2010affective factors influencing these decisions during genetic counseling.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Mothers (\n N<\/jats:italic>\n \u00a0=\u00a0282) reported on the perceived risks\/benefits of AYA disclosure. Multivariable regression identified predictors of disclosure, and paired\n t<\/jats:italic>\n \u2010tests evaluated changes over time in maternal\u2010AYA communication, distress, and decisional conflict following genetic counseling.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Mothers reported valuing the benefits of disclosure more than risks (\n p<\/jats:italic>\n \u00a0<\u00a00.001). Those who valued disclosure tended to have female (\n t<\/jats:italic>\n \u00a0=\u00a0\u22121.74,\n p<\/jats:italic>\n \u00a0=\u00a00.08) and older (\n r<\/jats:italic>\n \u00a0=\u00a00.14,\n p<\/jats:italic>\n \u00a0=\u00a00.03) children but were less knowledgeable about cancer risk (\n r<\/jats:italic>\n \u00a0=\u00a0\u22120.17,\n p<\/jats:italic>\n \u00a0=\u00a00.005). Conversely, mothers who perceived disclosure to AYAs as riskier tended to be non\u2010white (\n t<\/jats:italic>\n \u00a0=\u00a01.80,\n p<\/jats:italic>\n \u00a0=\u00a00.072), Hispanic (\n t<\/jats:italic>\n \u00a0=\u00a01.66,\n p<\/jats:italic>\n \u00a0=\u00a00.098), lower\u2010income (\n t<\/jats:italic>\n \u00a0=\u00a02.56,\n p<\/jats:italic>\n \u00a0=\u00a00.011), and with younger children (\n r<\/jats:italic>\n \u00a0=\u00a0\u22120.28,\n p<\/jats:italic>\n \u00a0<\u00a00.001) in poorer mental health (\n r<\/jats:italic>\n \u00a0=\u00a00.12,\n p<\/jats:italic>\n \u00a0=\u00a00.047). These findings were reaffirmed though a multivariable regression model controlling for benefits (adjusted\n R<\/jats:italic>\n 2<\/jats:sup>\n \u00a0=\u00a00.11; age\n B<\/jats:italic>\n \u00a0=\u00a0\u22121.09,\n p<\/jats:italic>\n \u00a0<\u00a00.001; mental health\n B<\/jats:italic>\n \u00a0=\u00a00.36,\n p<\/jats:italic>\n \u00a0=\u00a00.04). Post\u2010counseling, participants showed reduced decisional conflict (\n t<\/jats:italic>\n \u00a0=\u00a02.4,\n p<\/jats:italic>\n \u00a0=\u00a00.009) but increased depression\/anxiety (\n t<\/jats:italic>\n \u00a0=\u00a0\u22121.4,\n p<\/jats:italic>\n \u00a0=\u00a00.08) and lower parent\u2010child relationship quality (\n t<\/jats:italic>\n \u00a0=\u00a02.7,\n p<\/jats:italic>\n \u00a0<\u00a00.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Clinicians should be attuned to the factors shaping parental disclosure decisions and consider offering additional support to manage distress. Tailored educational tools for parents may aid family communication and improve psychosocial outcomes alongside genetic counseling.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/pon.70390","type":"journal-article","created":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T03:49:48Z","timestamp":1769226588000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Maternal Communication of\n BRCA<\/i>\n Risk to Adolescent and Young Adult Children: Implications for Supportive Care Intervention"],"prefix":"10.1002","volume":"35","author":[{"given":"Muriel R.","family":"Statman","sequence":"first","affiliation":[{"name":"Georgetown University Lombardi Comprehensive Cancer Center Washington District of Columbia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Marcelo M.","family":"Sleiman","sequence":"additional","affiliation":[{"name":"Georgetown University Lombardi Comprehensive Cancer Center Washington District of Columbia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beth N.","family":"Peshkin","sequence":"additional","affiliation":[{"name":"Georgetown University Lombardi Comprehensive Cancer Center Washington District of Columbia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8377-4666","authenticated-orcid":false,"given":"Jada G.","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiffani A.","family":"DeMarco","sequence":"additional","affiliation":[{"name":"Inova Health System Fairfax Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huma Q.","family":"Rana","sequence":"additional","affiliation":[{"name":"Dana\u2010Farber Cancer Institute Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judy E.","family":"Garber","sequence":"additional","affiliation":[{"name":"Dana\u2010Farber Cancer Institute Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosalba","family":"Sacca","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Ovadia","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudine","family":"Isaacs","sequence":"additional","affiliation":[{"name":"Georgetown University Lombardi Comprehensive Cancer Center Washington District of Columbia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0274-556X","authenticated-orcid":false,"given":"Kenneth P.","family":"Tercyak","sequence":"additional","affiliation":[{"name":"Georgetown University Lombardi Comprehensive Cancer Center Washington District of Columbia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,23]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"\u201cBreast Cancer Statistics | How Common is Breast Cancer? 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