{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T20:27:39Z","timestamp":1783110459358,"version":"3.54.6"},"reference-count":50,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Given that cancer survivors often face psychological problems, this study explores the effect of acceptance and commitment therapy (ACT) to improve death anxiety (DA), experiential avoidance (EA), meaning in life (MIL), and quality of life (QoL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study was conducted from June to November 2023, encompassing recruitment, an 8\u2010week intervention (July\u2013August 2023), and follow\u2010up to 3\u00a0months post\u2010intervention at a tertiary cancer hospital in China. A total of 50 cancer survivors were randomized (25 per group). The weekly intervention was delivered through in\u2010person, one\u2010on\u2010one sessions over 8\u00a0weeks. Each session (approximately 35\u201345\u00a0min) was structured to cover distinct thematic modules of ACT. The primary outcome was DA and other secondary outcomes included EA, MIL, as well as QoL. Data were collected at T0 (pre\u2010intervention), T1 (post\u2010intervention), T2 (1\u00a0month post\u2010intervention), and T3 (3\u00a0months post\u2010intervention). The intervention effects were estimated using generalized estimating equation models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Participants had various cancer types, primarily head and neck (28%), lung (28%), and breast (24%). Cancer stages included I\u2013II (54%), III (44%), and IV (2%). Participants in the ACT group revealed significantly greater reductions on DA than those in the wait\u2010list control group at T1 (95% CI: \u22123.449 to \u22122.631), T2 (95% CI: \u22124.899 to \u22123.821), and T3 (95% CI: \u22125.311 to \u22123.969), as well as on EA and the symptom domain of quality of life at three time points. In addition, the intervention demonstrated significantly greater improvements on MIL, the functional domain and global health status of quality of life at T1, T2, and T3.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this study with a wait\u2010list control group rather than an active comparator, the in\u2010person ACT\u2010based intervention reduced death anxiety, experiential avoidance, and symptom\u2010related quality of life impairments while enhancing meaning in life, functional quality of life, and global health status in cancer survivors. These benefits were sustained for up to 3\u00a0months post\u2010intervention, though generalizability may be limited by the sample's cancer types and stages.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      Chinese Clinical Trial Registry (ChiCTR2300074472).\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.chictr.org.cn\/\">https:\/\/www.chictr.org.cn\/<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pon.70492","type":"journal-article","created":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T07:04:59Z","timestamp":1781852699000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of Acceptance and Commitment Therapy on Death Anxiety in Cancer Survivors: A Randomized Controlled Trial"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3722-246X","authenticated-orcid":false,"given":"Furong","family":"Chen","sequence":"first","affiliation":[{"name":"The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University\/Hunan Cancer Hospital  Changsha Hunan Province China"},{"name":"School of Nursing University of South China  Hengyang Hunan Province China"},{"name":"School of Nursing Guangzhou Medical University  Guangzhou Guangdong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhirui","family":"Xiao","sequence":"additional","affiliation":[{"name":"School of Nursing University of South China  Hengyang Hunan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3740-3881","authenticated-orcid":false,"given":"Qihan","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Nursing Guangzhou Medical University  Guangzhou Guangdong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1747-2416","authenticated-orcid":false,"given":"Ying","family":"Xiong","sequence":"additional","affiliation":[{"name":"School of Nursing Guangzhou University of Chinese Medicine  Guangzhou Guangdong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanting","family":"Xia","sequence":"additional","affiliation":[{"name":"The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University\/Hunan Cancer Hospital  Changsha Hunan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyao","family":"Yan","sequence":"additional","affiliation":[{"name":"The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University\/Hunan Cancer Hospital  Changsha Hunan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4437-3947","authenticated-orcid":false,"given":"Zengjie","family":"Ye","sequence":"additional","affiliation":[{"name":"School of Nursing Guangzhou Medical University  Guangzhou Guangdong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meijun","family":"Ou","sequence":"additional","affiliation":[{"name":"The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University\/Hunan Cancer Hospital  Changsha Hunan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianghua","family":"Xu","sequence":"additional","affiliation":[{"name":"The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University\/Hunan Cancer Hospital  Changsha Hunan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,19]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.70077"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4783"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.7314\/apjcp.2012.13.5.2405"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjspcare\u20102012\u2010000420"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888\u2010024\u201005819\u20108"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1348\/135910707x272790"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2022.07.015"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4168"},{"key":"e_1_2_15_10_1","article-title":"Experiential Avoidance in Advanced Cancer: A Mixed\u2010Methods Systematic Review","author":"S Davis M. 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