{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T20:39:02Z","timestamp":1790195942939,"version":"4.1.0"},"reference-count":122,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T00:00:00Z","timestamp":1780099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T00:00:00Z","timestamp":1780099200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82073407"],"award-info":[{"award-number":["82073407"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Fear of cancer recurrence (FCR) is one of the most prevalent psychological burdens among cancer patients and exerts a substantial negative impact on their quality of life and overall well\u2010being. Although various psychological interventions have demonstrated promise in alleviating FCR, their comparative effectiveness remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To conduct an up\u2010to\u2010date systematic review and network meta\u2010analysis to compare the relative efficacy of psychological interventions for alleviating FCR in cancer patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Six electronic databases were systematically searched from inception to October 2025 to identify randomized controlled trials comparing psychological interventions with each other or with control conditions. Two investigators independently conducted study selection, data extraction, and risk\u2010of\u2010bias assessment using the Cochrane RoB 2.0 tool. Pairwise meta\u2010analyses and a frequentist random\u2010effects network meta\u2010analysis were performed using Review Manager 5.4, R 4.4.0, and STATA 14.0. Interventions were ranked using the Surface Under the Cumulative Ranking Curve (SUCRA). The protocol was registered with PROSPERO (CRD42023414987).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixty\u2010one randomized controlled trials involving 6932 patients and 10 psychological interventions were included in the network meta\u2010analysis. Cancer and living meaningfully interventions (SMD ranged from \u22121.78 to \u22122.68), comprehensive therapy (SMD ranged from \u22120.97 to \u22121.67), mindful\u2010ness\u2010based interventions(SMD\u00a0=\u00a0\u22120.90; 95%CrI [\u22121.56, \u22120.24]), and cognitive behavioral therapy(SMD\u00a0=\u00a0\u22120.71; 95%CrI [\u22121.18, \u22120.23]) were superior to control comparisons for improving FCR. Subgroup analyses showed that face\u2010to\u2010face delivery formats and longer intervention durations were consistently associated with greater effectiveness. Global and local consistency diagnostics indicated good model fit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Cancer and living meaningfully, comprehensive therapy, acceptance and commitment therapy, mindfulness\u2010based interventions and cognitive behav\u2010ioural therapy are the most efficacious psychological interventions for reducing FCR and should be prioritized in clinical care. Clinicians should consider implementing interventions delivered face\u2010to\u2010face and of longer duration to maximize therapeutic benefits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pon.70509","type":"journal-article","created":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T13:05:36Z","timestamp":1780146336000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effectiveness Comparisons of Various Psychological Therapies for Fear of Cancer Recurrence in Cancer Patients: A Systematic Review and Network Meta\u2010Analysis"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-5927-306X","authenticated-orcid":false,"given":"Ting","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Gastric Surgery the First Affiliated Hospital with Nanjing Medical University  Nanjing 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