{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:52:26Z","timestamp":1786978346726,"version":"build-2736575974"},"reference-count":42,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T00:00:00Z","timestamp":1780704000000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Fear of progression (FoP) represents a significant psychological burden for pediatric cancer patients and their parents. This study investigates FoP levels across acute treatment (AcT) and follow\u2010up care (FuC) and examines trajectories over time, associated sociodemographic factors, and parent\u2010child associations. It also proposes clinically relevant thresholds for psychosocial care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 171 patient\u2013parent dyads participated in a cross\u2010sectional and longitudinal study. Children aged 7\u201318 and one parent per child completed the Fear of Progression Questionnaire\u2014Short Form (FoP\u2010Q\u2010SF). Data were collected during AcT (two time points) and FuC. Statistical analyses included nonparametric tests and correlation analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>FoP levels were significantly lower during FuC compared to AcT for both children and parents, and parental FoP decreased over the 1\u2010year follow\u2010up period. Parents consistently showed higher FoP than their children, and a significant parent\u2013child correlation emerged in FuC. FoP was higher in girls and was positively associated with child age and negatively associated with parent age. Using suggested thresholds, 57.8% of parents showed dysfunctional FoP. Among children, 45.2% reported low, 40% moderate, and 14.8% high FoP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although levels of FoP are lower in FuC than in AcT, they remain a prevalent burden\u2014particularly for younger parents, older children, and girls. The observed parent\u2010child associations highlight the need for family\u2010oriented psychosocial care. A proposed three\u2010stage cut\u2010off (low, moderate, high FoP) may guide clinical decision\u2010making and support tailored treatment strategies. Routine screening and preventive approaches are recommended to mitigate FoP and its potential intergenerational transmission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      The study has been pre\u2010registered at the German Clinical Trials Register (DRKS 00022034, registered 29\n                      <jats:sup>th<\/jats:sup>\n                      of June 2020) and at the Open Science Foundation (\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/osf.io\/fuahc\">https:\/\/osf.io\/fuahc<\/jats:ext-link>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pon.70514","type":"journal-article","created":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T10:00:16Z","timestamp":1780740016000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Fear of Progression in Pediatric Cancer Patients and Their Parents: Trajectories, Prevalence, and Correlates Across Acute Treatment and Follow\u2010Up Care"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4286-7414","authenticated-orcid":false,"given":"Jessy","family":"Herrmann","sequence":"first","affiliation":[{"name":"Department of Pediatric Oncology Haematology and Haemostaseology Leipzig University  Leipzig Germany"},{"name":"Registered Association for parents of children with cancer Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2902-0171","authenticated-orcid":false,"given":"Kristina","family":"Herzog","sequence":"additional","affiliation":[{"name":"Department of Paediatric Oncology and Haematology University Hospital Carl Gustav Carus Dresden  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9524-8257","authenticated-orcid":false,"given":"Julia","family":"Martini","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Psychotherapy Faculty of Medicine of the Technische Universit\u00e4t Dresden  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Santel","sequence":"additional","affiliation":[{"name":"Registered Association for parents of children with cancer Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9754-0411","authenticated-orcid":false,"given":"Leonard Konstantin","family":"Kulisch","sequence":"additional","affiliation":[{"name":"Mental Health Research and Treatment Centre (FBZ), Faculty of Psychology Ruhr\u2010University Bochum and German Center for Mental Health (DZPG)  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1739-1090","authenticated-orcid":false,"given":"J\u00f6rn\u2010Sven","family":"K\u00fchl","sequence":"additional","affiliation":[{"name":"Department of Pediatric Oncology Haematology and Haemostaseology Leipzig University  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7656-5556","authenticated-orcid":false,"given":"Florian","family":"Schepper","sequence":"additional","affiliation":[{"name":"Department of Pediatric Oncology Haematology 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