{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T11:06:22Z","timestamp":1785323182387,"version":"3.55.0"},"reference-count":78,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T00:00:00Z","timestamp":1783382400000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Sarcoma is a rare and heterogeneous cancer frequently associated with significant psychosocial burden. This review aims to synthesise qualitative research to examine the psychosocial impact of sarcoma in adults, focusing on how individuals experience and make sense of disruption across diagnosis, treatment, recovery, and survivorship, the ways they adapt to these challenges, and the psychosocial needs they identify throughout the sarcoma trajectory.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A preregistered systematic review (PROSPERO CRD42024571502) was conducted following PRISMA and ENTREQ guidance. Four databases were searched (PsycINFO, MEDLINE, CINAHL, and Web of Science), and peer\u2010reviewed qualitative studies involving adults with sarcoma were included. Updated search conducted on 30\/12\/2025. Study quality was appraised using CASP, and data were synthesised using inductive thematic synthesis to integrate experiential accounts and generate analytical insights.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Forty studies published between 2008 and 2025 involving 538 participants were included, with most rated high methodological quality. Five themes captured sarcoma as a cumulative psychosocial disruption, beginning with diagnostic delay and uncertainty, intensifying through invasive treatment and prolonged recovery, and extending into enduring changes in body image, function, identity, and social participation. Adaptation emerged as a dynamic, ongoing process involving self\u2010management, meaning\u2010making, selective information engagement, and reliance on relational and professional support. Persistent unmet needs were identified, particularly regarding specialist, coordinated care and sarcoma\u2010informed rehabilitation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Experiences of sarcoma as adults are characterised by prolonged psychosocial disruption requiring adaptation across all stages of the illness. Findings highlight the importance of specialist, continuous, and rehabilitation\u2010focused sarcoma care to support long\u2010term adjustment and wellbeing.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pon.70534","type":"journal-article","created":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T14:28:59Z","timestamp":1783434539000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychosocial Impact of Sarcoma: Challenges and\u00a0Adaptation, a Meta\u2010Synthesis"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7977-7853","authenticated-orcid":false,"given":"R.","family":"Beghean","sequence":"first","affiliation":[{"name":"University College Cork (UCC), School of Applied Psychology  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8897-2204","authenticated-orcid":false,"given":"L.","family":"O'Driscoll","sequence":"additional","affiliation":[{"name":"St. Vincent's University Hospital (SVUH)  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Ryan","sequence":"additional","affiliation":[{"name":"University College Cork (UCC), School of Applied Psychology  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5504-7824","authenticated-orcid":false,"given":"P.","family":"Carty","sequence":"additional","affiliation":[{"name":"University College Cork (UCC), School of Applied Psychology  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3838-9165","authenticated-orcid":false,"given":"F.","family":"Larkin","sequence":"additional","affiliation":[{"name":"University College Cork (UCC), School of Applied Psychology  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8233-8124","authenticated-orcid":false,"given":"F.","family":"O'Keeffe","sequence":"additional","affiliation":[{"name":"University College Cork (UCC), School of Applied Psychology  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,7]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2022.871254"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2021.101897"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/2053434520907743"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/6868030"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102018\u2010028693"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5007"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.6240"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1166838"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5411"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9730867"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.70174"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2025.102890"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1017\/S095457942100002X"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/11786329241278814"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119536604.ch21"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102288\u201012\u2010181"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102288\u20108\u201045"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.20892\/j.issn.2095\u20103941.2019.0041"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/jncimonographs\/lgae017"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13643\u2010016\u20100384\u20104"},{"key":"e_1_2_11_23_1","unstructured":"Critical Appraisal Skills Programme \u201cCASP Qualitative Studies Checklist. CASP Qualitative Studies Checklist \u201d (2024) [Internet] https:\/\/casp\u2010uk.net\/casp\u2010tools\u2010checklists\/qualitative\u2010studies\u2010checklist\/."},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/2632084320947559"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/wvn.12134"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2024.102585"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1188\/19.ONF.493\u2010502"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2021.102062"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1089\/jayao.2015.0024"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.994934"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010023\u201008149\u20109"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers17030442"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-025-09199-x"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12955\u2010022\u201001971\u20105"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2024.2393440"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1080\/09593985.2018.1519622"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41687\u2010022\u201000450\u20101"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/484196"},{"key":"e_1_2_11_39_1","article-title":"Negative and Positive Consequences of Cancer Treatment Experienced by Long\u2010Term Osteosarcoma Survivors: A Qualitative Study","author":"Fauske L.","year":"2015","journal-title":"Anticancer Research"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.24138"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.13119"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1080\/17482631.2025.2597584"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0210731"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjspcare\u20102015\u2010000898"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol32120691"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1155\/ecc\/5633734"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9581781"},{"key":"e_1_2_11_48_1","unstructured":"J.Kain A.Carlson J.Kahler J.Bemboom K.McDonald andB.Miller Lessons And Advice From Our Patients: A Focus Group of Sarcoma Survivors(2017)."},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.25915"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10225334"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1080\/28352610.2025.2473316"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19053112"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15153946"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1097\/NCC.0000000000001163"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2008.09.011"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.70257"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0243439"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2008.03.001"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1080\/07347332.2018.1498425"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.12667"},{"key":"e_1_2_11_61_1","article-title":"Factors Influencing Functional Recovery After Limb\u2010Salvage Surgery for Lower Extremity Musculoskeletal Tumours: A Qualitative Study Combining Patients\u2019 and Healthcare Professionals\u2019 Perspectives","author":"van Kouswijk H. W.","year":"2024","journal-title":"Disability & Rehabilitation"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.2340\/jrm.v57.34888"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5349"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002820\u2010199904000\u201000002"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2024.2393440"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjspcare\u20102015\u2010000898"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2024.102631"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00402\u2010014\u20102086\u20105"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40271\u2010016\u20100200\u20101"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12904\u2010018\u20100346\u20109"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.esmorc.2024.100001"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15030956"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2022.995981"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010021\u201006253\u20102"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.3390\/children12111464"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102020\u2010038799"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers17111861"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.2147\/PROM.S130183"},{"key":"e_1_2_11_79_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2024.2422471"}],"container-title":["Psycho-Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pon.70534","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/pon.70534","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pon.70534","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T10:48:39Z","timestamp":1785322119000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pon.70534"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":78,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/pon.70534"],"URL":"https:\/\/doi.org\/10.1002\/pon.70534","archive":["Portico"],"relation":{},"ISSN":["1057-9249","1099-1611"],"issn-type":[{"value":"1057-9249","type":"print"},{"value":"1099-1611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-03-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70534"}}