{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:56:15Z","timestamp":1790618175076,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Psycho-Oncology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Adolescents with osteosarcoma face clinical and psychosocial challenges during the transition from adolescence to adulthood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      This study examined the effects of a nurse\u2010navigated game\u2010based intervention (N\n                      <jats:sup>2<\/jats:sup>\n                      \u2010GBI) on transition readiness in adolescents.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Participants in the control group received usual care, whereas the intervention group received the N\n                      <jats:sup>2<\/jats:sup>\n                      \u2010GBI programme alongside usual care. Transition readiness was assessed using the Self\u2010Management and Transition to Adulthood with Rx\u00a0=\u00a0Treatment Questionnaire as the primary outcome. Secondary outcomes included cancer worry, transition expectation and patient activation, which were measured using the Cancer Worry Scale, Transition Expectation Scale, and Patient Activation Measure, respectively. Outcomes were assessed at baseline (T0), immediately after intervention (T1) and at 12\u2010week follow\u2010up (T2). Generalized estimating equations were used to estimate the intervention effects.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 59 adolescents were enrolled. The intervention and control groups comprised 32 and 27 adolescents, respectively, with mean ages of 15 and 13\u00a0years, respectively. A total of 19 and 15 participants were male in the intervention and control groups, respectively. Compared with the control group, the N\n                      <jats:sup>2<\/jats:sup>\n                      \u2010GBI group showed significantly greater improvement in transition readiness at T1 (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a08.83,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) and T2 (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a07.97,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.001). The N\n                      <jats:sup>2<\/jats:sup>\n                      \u2010GBI programme also significantly reduced cancer worry (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.009) and increased patient activation (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.001), but had no significant effect on transition expectation (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.056).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The N\n                      <jats:sup>2<\/jats:sup>\n                      \u2010GBI programme improved transition readiness, reduced cancer worry, and increased patient activation among adolescents with osteosarcoma, but did not significantly improve transition expectation. This intervention may be a useful nurse\u2010led approach to transition preparation in pediatric oncology care. Future studies with larger sample sizes and prolonged follow\u2010up durations are needed.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pon.70591","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T12:56:01Z","timestamp":1788353761000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of a Nurse\u2010Navigated Game\u2010Based Program on Transition Readiness and Psychosocial Outcomes in Adolescents With Osteosarcoma: A Cluster\u2010Nonrandomized Controlled Study"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1646-3558","authenticated-orcid":false,"given":"Jun","family":"Ma","sequence":"first","affiliation":[{"name":"Nursing and Materials Medical Engineering Interdisciplinary Research Laboratory West China Hospital Sichuan University  Chengdu China"},{"name":"Xiangya School of Nursing Central South University  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Obstetrical Nursing West China Second Hospital Sichuan University  Chengdu China"},{"name":"Key Laboratory of Birth Defects and Related Diseases of Women and Children Sichuan University Ministry of Education  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2449-1276","authenticated-orcid":false,"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Xiangya School of Nursing Central South University  Changsha China"},{"name":"Teaching and Research Section of Clinical Nursing Xiangya Hospital Central South University  Changsha China"},{"name":"Mobile Health Ministry of Education\u2010China Mobile Joint Laboratory Xiangya Hospital Central South University  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9299-8925","authenticated-orcid":false,"given":"Fei","family":"Liu","sequence":"additional","affiliation":[{"name":"Teaching and Research Section of Clinical Nursing Xiangya Hospital Central South University  Changsha China"},{"name":"Health Management Center Xiangya Hospital Central South University  Changsha Hunan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,2]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"Childhood Cancer [Internet]","author":"World Health 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