{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T12:02:39Z","timestamp":1790942559787,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2003,11,10]],"date-time":"2003-11-10T00:00:00Z","timestamp":1068422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2003,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    An epidemic rise in asthma has occurred concurrently with a rise in overweight among United States children, but it is unclear whether body weight affects the risk of incident childhood asthma. We studied the prospective relation of body\u2010mass index (BMI) to incident asthma in a longitudinal study of 9,828 children aged 6\u201314 years, examined annually over a median follow\u2010up time of 5 years in six US cities. An increased risk of a new asthma diagnosis in girls was associated with higher BMI at entry into the study (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.009) and greater increase in BMI during follow\u2010up (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009=\u20090.0003). Compared with girls in the leanest quintile of BMI at entry (age taken into account), girls in the top quintile of adiposity had 2.2 times greater risk of incident asthma with any wheeze in subsequent years. Girls with the largest annual rate of increase in BMI (top compared to bottom quintile, age taken into account) had 1.5 times the risk of asthma with any wheeze, and 2.2 times the risk of asthma with persistent wheeze. Boys with the largest and smallest annual changes in BMI also had an increased risk of asthma. For girls, overweight contributes to development of asthma. For boys and girls, extremes of annual BMI growth rates increase the risk of asthma. Pediatr Pulmonol. 2003; 36:514\u2013521. \u00a9 2003 Wiley\u2010Liss, Inc.\n                  <\/jats:p>","DOI":"10.1002\/ppul.10376","type":"journal-article","created":{"date-parts":[[2003,11,12]],"date-time":"2003-11-12T09:56:00Z","timestamp":1068630960000},"page":"514-521","source":"Crossref","is-referenced-by-count":192,"title":["Body\u2010mass index as a predictor of incident asthma in a prospective cohort of children"],"prefix":"10.1002","volume":"36","author":[{"given":"Diane R.","family":"Gold","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew I.","family":"Damokosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas W.","family":"Dockery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine S.","family":"Berkey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,11,10]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/10408399309527636"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1996.02170290022003"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.54.5.396"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/148.1.10"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/142.3.555"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.1999.00455.x"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.160.1.9807104"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.6.2006140"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1093\/ajcn\/70.1.123s","article-title":"Introduction: the use of body mass index to assess obesity in children","volume":"70","author":"Dietz WH","year":"1999","journal-title":"Am J Clin Nutr"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(98)70434-2"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.105.4.e56"},{"key":"e_1_2_1_13_2","unstructured":"KuczmarksiRJ OgdenCL Grummer\u2010StrawnLM et al.CDC growth charts: US advance data from vital and health statistics no. 314: National Center for Health Statistics 2000. Available at:http:\/\/www.cdc.gov\/nchs\/about\/major\/nhanes\/growthcharts\/ bmiage.txt"},{"key":"e_1_2_1_14_2","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life\u2010tables","volume":"34","author":"Cox DR","year":"1972","journal-title":"J R Stat Soc Ser B"},{"key":"e_1_2_1_15_2","unstructured":"1997 SAS Institute Inc. Cary NC SAS Institute SAS\/STAT software: changes and enhancements through release 6.12 (Proc phreg)"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.149.5.8173760"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1950150204"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1381\/096089299765552981"},{"key":"e_1_2_1_19_2","first-page":"339","article-title":"Dysynapsis in normal lungs assessed by the relationship between maximal flow, static recoil, and vital capacity","volume":"121","author":"Mead J","year":"1980","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_1_20_2","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1093\/jn\/127.9.1917S","article-title":"Potential role of TNF alpha and lipoprotein lipase as candidate genes for obesity","volume":"127","author":"Kern PA","year":"1997","journal-title":"J Nutr"},{"key":"e_1_2_1_21_2","first-page":"353","volume-title":"Asthma","author":"Shimizu Y","year":"1997"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.56.11.835"},{"key":"e_1_2_1_23_2","first-page":"150","article-title":"Body mass index and asthma in children age 9\u201314","volume":"159","author":"Camargo CA","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.21.2582"},{"key":"e_1_2_1_25_2","first-page":"4","article-title":"Women's health issues in pulmonary medicine","volume":"14","author":"Gold DR","year":"1997","journal-title":"Pulmon Perspect"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.152.4.7551368"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/87.17.1297"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1159\/000225731"},{"key":"e_1_2_1_29_2","doi-asserted-by":"crossref","first-page":"3469","DOI":"10.1210\/jcem.83.10.5204","article-title":"Effect of obesity on estradiol level, and its relationship to leptin, bone maturation, and bone mineral density in children","volume":"83","author":"Klein KO","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199609263351304"},{"key":"e_1_2_1_31_2","doi-asserted-by":"publisher","DOI":"10.1159\/000191265"},{"key":"e_1_2_1_32_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199910073411501"},{"key":"e_1_2_1_33_2","first-page":"131","article-title":"The relationship of body mass index with methacholine airway hyperresponsiveness in middle\u2010aged and older men","volume":"159","author":"Litonjua AA","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"e_1_2_1_34_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.164.10.2105033"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.10376","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.10376","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,14]],"date-time":"2024-12-14T05:22:08Z","timestamp":1734153728000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.10376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,11,10]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2003,12]]}},"alternative-id":["10.1002\/ppul.10376"],"URL":"https:\/\/doi.org\/10.1002\/ppul.10376","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,11,10]]}}}