{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:44:27Z","timestamp":1756464267608},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,1,12]],"date-time":"2004-01-12T00:00:00Z","timestamp":1073865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2004,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 12\u2010year\u2010old boy presented with left shoulder pain during physical exercise and complained of uncommon sweating and fatigue. Diagnostic evaluation revealed a solitary pulmonary nodule in the left upper lobe. All laboratory values were within normal limits, except for an elevated level of antineutrophil cytoplasmic antibodies directed against myeloperoxidase (p\u2010ANCA). Surgery was performed, and pathological examination showed a localized granulomatous vasculitis. Antineutrophil cytoplasmic antibodies directed against affinity purified proteinase 3 (p\u2010ANCA) concentrations returned to baseline within 6 months, and the patient has done well during a follow\u2010up period of 2 years. While nodular vasculitis is known to occur in Wegener's granulomatosis, to the best of our knowledge, this case represents the first c\u2010ANCA negative primary pulmonary vasculitis in childhood. Pediatr Pulmonol. 2004; 37:181\u2013185. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ppul.10412","type":"journal-article","created":{"date-parts":[[2004,1,13]],"date-time":"2004-01-13T12:01:44Z","timestamp":1073995304000},"page":"181-185","source":"Crossref","is-referenced-by-count":2,"title":["Nodular pulmonary vasculitis in a twelve\u2010year\u2010old boy"],"prefix":"10.1002","volume":"37","author":[{"given":"T.","family":"Borchers","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Dirsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Schaper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Kreuzfelder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Jakob","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Ratjen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,1,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)60664-9"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S0033-8389(22)02611-2","article-title":"Nodules, masses and pseudomasses in the pediatric lung","volume":"31","author":"Eggli KD","year":"1993","journal-title":"Radiol Clin North Am"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780370206"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-89-5-660"},{"key":"e_1_2_1_6_2","first-page":"319","article-title":"Classification of vasculitides","volume":"24","author":"Leu HJ","year":"1995","journal-title":"Vasa"},{"key":"e_1_2_1_7_2","volume-title":"Systemic vasculitides","author":"Churg A","year":"1991"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200106000-00018"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-123-12-199512150-00005"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/00000478-198004010-00002","article-title":"Solitary necrotizing granulomas of the lung: differentiating features and etiology","volume":"4","author":"Ulbright TM","year":"1980","journal-title":"Am J Surg Pathol"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(66)90214-2"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(70)80029-8"},{"key":"e_1_2_1_13_2","first-page":"162","article-title":"Unilaterally multiplying and migrating pulmonary masses: first manifestation of limited Wegener's granulomatosis","volume":"79","author":"Dechambre S","year":"1996","journal-title":"J Belge Radiol"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(85)91147-X"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(12)80521-X"},{"key":"e_1_2_1_16_2","first-page":"11","article-title":"Immunodiagnostic and pathophysiologic aspects of antineutrophil cytoplasmic antibodies in vasculitis","volume":"7","author":"Gross WL","year":"1995","journal-title":"Curr Opin Rheumatol"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(92)90202-M"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(12)80695-0"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(93)90295-R"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004310050983"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/104.1.7"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1989.00390110055012"},{"key":"e_1_2_1_23_2","first-page":"309","article-title":"Sequential antineutrophil cytoplasm antibody titres in the management of systemic vasculitis","volume":"3","author":"Jayne D","year":"1990","journal-title":"Nephrol Dial Transplant"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.94.07071365"},{"key":"e_1_2_1_25_2","first-page":"219","article-title":"Antineutrophil cytoplasmic antibody (cANCA and pANCA) titers in relation to disease activity in patients with necrotizing vasculitis: a longitudinal study","volume":"5","author":"Pettersson E","year":"1992","journal-title":"Clin Nephrol"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.70.3.384"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004670050043"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.79.3.246"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcpc020022"},{"key":"e_1_2_1_30_2","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1002\/art.1780330806","article-title":"The American College of Rheumatology 1990 criteria for the classification of the Churg\u2010Strau\u00df\u2010syndrome (allergic granulomatosis and angiitis)","volume":"33","author":"Mansi AT","year":"1990","journal-title":"Arthritis Rheum"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.10412","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.10412","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.10412","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T22:08:40Z","timestamp":1705010920000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.10412"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1,12]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,2]]}},"alternative-id":["10.1002\/ppul.10412"],"URL":"https:\/\/doi.org\/10.1002\/ppul.10412","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,1,12]]}}}