{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T20:38:43Z","timestamp":1760819923473},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,10,20]],"date-time":"2005-10-20T00:00:00Z","timestamp":1129766400000},"content-version":"vor","delay-in-days":7173,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[1986,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Primary central alveolar hypoventilation (PCAH) has been described in adults, children, and infants. It is usually diasnosed clinically at an advanced stage when the secondary effects of chronic hypoxia and hypercapnia become evident. We report here PCAH in its early stage in a 7\u2010year\u2010old child, whose disease appeared as acute respiratory failure during an acute illness. When the acute illness subsided, the salient features of PCAH remained and were studied in some detail. We also describe the child's response to respiratory stimuli, and some results related to endorphins, including his plasma endorphin levels and response to a trial of naloxone.<\/jats:p>","DOI":"10.1002\/ppul.1950020211","type":"journal-article","created":{"date-parts":[[2007,3,6]],"date-time":"2007-03-06T11:39:53Z","timestamp":1173181193000},"page":"114-118","source":"Crossref","is-referenced-by-count":2,"title":["Primary central alveolar hypoventilation in a child: Early diagnosis during acute illness; trials with respiratory stimuli; studies related to endorphins"],"prefix":"10.1002","volume":"2","author":[{"given":"Immanuela R.","family":"Moss","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Cataletto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giora E.","family":"Winnik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(55)90162-5"},{"key":"e_1_2_1_3_2","first-page":"557","article-title":"Central alveolar hypoventilation: A case report","volume":"103","author":"Naughton J","year":"1971","journal-title":"Am Rev Resp Dis"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0272-5231(21)00056-3","article-title":"Primary alveolar hypoventilation","volume":"1","author":"Reichel J","year":"1980","journal-title":"Clin Chest Med"},{"key":"e_1_2_1_5_2","first-page":"259","article-title":"Central alveolar hypoventilation in a child: An evaluation using a whole body plethysmograph","volume":"112","author":"Nattie EE","year":"1975","journal-title":"Am Rev Res Dis"},{"key":"e_1_2_1_6_2","first-page":"23","article-title":"Central hypoventilation syndrome: Experience with bilateral phrenic nerve pacing in 3 neonates","volume":"118","author":"Hunt CE","year":"1978","journal-title":"Am Rev Res Dis"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80082-6"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/imj.1967.16.1.20"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(75)90059-6"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1152\/jappl.1972.32.1.44","article-title":"Hypoxic and hypercapnic ventilatory drives in children native to high altitude","volume":"32","author":"Byrne Quinn E","year":"1972","journal-title":"J Appl Physiol"},{"key":"e_1_2_1_11_2","first-page":"141","article-title":"Idiopathic hypoventilation syndrome: Importance of preventing noctural hypoxemia and hypercapnia","volume":"121","author":"Barlow PB","year":"1980","journal-title":"Am Rev Resp Dis"},{"key":"e_1_2_1_12_2","first-page":"157","article-title":"A polygraphic study of one case of primary alveolar hypoventilation (Ondine's curse)","volume":"20","author":"Coccagna C","year":"1984","journal-title":"Bull Eur Physiopathol Resp"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.910138"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(84)90055-0"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.1950020211","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.1950020211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T22:56:25Z","timestamp":1697842585000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.1950020211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,3]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1986,3]]}},"alternative-id":["10.1002\/ppul.1950020211"],"URL":"https:\/\/doi.org\/10.1002\/ppul.1950020211","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,3]]}}}