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The levels of all assayed neuroactive substances, metabolites, and amino acids, with one exception, were normal compared to an age\u2010matched group of neurologically healthy children. The levels of the dopamine metabolite homovanillic acid in the children with Ondine's curse were approximately 2.4 times higher than expected for age range. The present findings may indicate a link between central nervous system dopamine activity and chronic central alveolar hypoventilation. Among other possible explanations, the changes seen might represent a primary alteration in dopamine activity or may reflect a change in dopamine turnover resulting from the chronic hypoventilation. <jats:bold>Pediatr Pulmonol 1987; 3:131\u2013135<\/jats:bold>.<\/jats:p>","DOI":"10.1002\/ppul.1950030216","type":"journal-article","created":{"date-parts":[[2007,3,6]],"date-time":"2007-03-06T12:12:31Z","timestamp":1173183151000},"page":"131-135","source":"Crossref","is-referenced-by-count":8,"title":["Changes in cerebrospinal fluid homovanillic acid in children with Ondine's curse"],"prefix":"10.1002","volume":"3","author":[{"given":"J.","family":"Hedner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Hedner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. 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