{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:10:59Z","timestamp":1789179059615,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,12,12]],"date-time":"2005-12-12T00:00:00Z","timestamp":1134345600000},"content-version":"vor","delay-in-days":6555,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[1988,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Ventricular function was evaluated using radionuclide ventriculography in 27 children with oropharyngeal obstruction and clinical features of obstructive sleep apnea. Their mean age was 3.5 years (9 months to 7.5 years). Conventional clinical assessment did not detect cardiac involvement in 25 of 27 children; however, reduced right ventricular ejection fraction (less than 35%) was found in 10 (37%) patients (mean: 19.5 \u00b1 2.3% SE, range: 8\u201328%). In 18 patients wall motion abnormality was detected. In 11 children in whom radionuclide ventriculography was performed before and after adenotonsillectomy, right ventricular ejection fraction rose from 24.4 \u00b1 3.4% to 46.7 \u00b1 3.4% (P &lt; 0.005), and in all cases wall motion showed a definite improvement. In five children, left ventricular ejection fraction rose &gt; 10% after removal of oropharyngeal obstruction. It is concluded that right ventricular function may be compromised in children with obstructive sleep apnea secondary to adenotonsillar hypertrophy, even before clinical signs of cardiac involvement are present.<\/jats:p>","DOI":"10.1002\/ppul.1950040304","type":"journal-article","created":{"date-parts":[[2007,3,6]],"date-time":"2007-03-06T13:09:13Z","timestamp":1173186553000},"page":"139-143","source":"Crossref","is-referenced-by-count":198,"title":["Ventricular dysfunction in children with obstructive sleep apnea: Radionuclide assessment"],"prefix":"10.1002","volume":"4","author":[{"given":"Asher","family":"Tal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Leiberman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giora","family":"Margulis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaul","family":"Sofer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,12,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(65)80242-6"},{"key":"e_1_2_1_3_2","first-page":"164","article-title":"Reversible cor pulmonale due to hypertrophied tonsils and adenoids: Studies in two cases","volume":"32","author":"Noonan JA","year":"1965","journal-title":"Circulation"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1969.02100040710007"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.44.237.585"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(69)90378-6"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196709072771003"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.68.2.166"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00254324"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.93.1.119"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02240461"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(82)90050-9"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(84)80348-0"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1980.00790320044011"},{"key":"e_1_2_1_15_2","first-page":"987","article-title":"Radionuclide assessment of right and left ventricular function during bicyle exercise in young patients with cystic fibrosis","volume":"130","author":"Benson LN","year":"1984","journal-title":"Am Rev Respir Dis."},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80231-X"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.54.5.509"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197908303010901"},{"key":"e_1_2_1_19_2","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0272-5231(21)00197-0","article-title":"Effect of positive and negative pressure ventilation on cardiac performance","volume":"4","author":"Robotham JL","year":"1983","journal-title":"Clin Chest Med."},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.71.5.737"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1981.00340080025009"},{"key":"e_1_2_1_22_2","first-page":"82","article-title":"Continuous positive airway pressure for long\u2010term treatment of sleep apnea","volume":"138","author":"Schmidt\u2010Nowara WW","year":"1984","journal-title":"Am J Dis Child."},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)91043-3"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.1950040304","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.1950040304","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T09:45:03Z","timestamp":1697967903000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.1950040304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,1]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1988,1]]}},"alternative-id":["10.1002\/ppul.1950040304"],"URL":"https:\/\/doi.org\/10.1002\/ppul.1950040304","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,1]]}}}