{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T04:42:23Z","timestamp":1785818543269,"version":"3.56.0"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,12,12]],"date-time":"2005-12-12T00:00:00Z","timestamp":1134345600000},"content-version":"vor","delay-in-days":6555,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[1988,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The present study was designed to investigate the development of respiratory control during feeding in premature infants. Cardiorespiratory disturbances during feeding were evaluated with polygraphic monitoring in 24 premature infants within 1 week of beginning nipple feeds. During the initial study, 15 infants exhibited one or more episodes of short apnea (\u2265 10 sec) and three infants exhibited prolonged apnea (\u226520 sec). Bradycardia developed in seven infants; apnea and decreases in oxygen saturation invariably preceded the development of bradycardia. In contrast, short apnea occurred during sleep in five infants and associated bradycardia developed in four infants. Occurrence of apnea during sleep was significantly lower than that observed during feeding (<jats:italic>P<\/jats:italic> &lt; 0.05). Subsequently, 18 of these infants were reevaluated 7\u201310 days later. Seven infants developed one or more episodes of short apnea, five developed prolonged apnea, and four developed bradycardia. These occurrences were not significantly different from those observed during the initial study (<jats:italic>P<\/jats:italic> &gt; 0.05). Short apnea persisted during sleep in four infants during reevaluation. Most of the apneic episodes in both studies were mixed apnea. The high frequency of cardiorespiratory disturbances during the first 2 weeks of nipple feeding indicates that in most preterm infants respiratory control during feeding is still immature at the postconceptional age of 35\u201336 weeks.<\/jats:p>","DOI":"10.1002\/ppul.1950050408","type":"journal-article","created":{"date-parts":[[2007,3,6]],"date-time":"2007-03-06T13:20:54Z","timestamp":1173187254000},"page":"220-224","source":"Crossref","is-referenced-by-count":56,"title":["Respiratory control during nipple feeding preterm infants"],"prefix":"10.1002","volume":"5","author":[{"given":"Oommen P.","family":"Mathew","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,12,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(08)61273-X"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1982.62.1.129"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-3782(85)90100-8"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4899-5139-7_9"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(85)80363-2"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(83)80368-0"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1982.53.2.455"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.55.5.640"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1978.sp012281"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/137.1.113"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1981.50.4.851"},{"key":"e_1_2_1_13_2","first-page":"382A","article-title":"The development of respiratory control during oral feeding in premature infants (abstract)","volume":"20","author":"Pierantoni HR","year":"1986","journal-title":"Pediatr Res"},{"key":"e_1_2_1_14_2","first-page":"623","article-title":"Hypoxemia associated with feeding in the preterm infant and full term neonate","volume":"138","author":"Rosen CR","year":"1984","journal-title":"Am J Dis Child."},{"key":"e_1_2_1_15_2","first-page":"178","article-title":"Transient pharyngeal coordination in the newborn","volume":"111","author":"Frank MM","year":"1966","journal-title":"Am J Dis Child."},{"key":"e_1_2_1_16_2","unstructured":"BurnardED.Apnea cyanosis during feeding in the neonate. In: Proceedings of the Eighth Singapore\u2010Malasia Congress of Medicine.1973;220\u2013222."},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(85)80373-5"},{"key":"e_1_2_1_18_2","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1542\/peds.70.6.858","article-title":"Sudden infant death syndrome and apnea\/obstruction during neonatal sleep and feeding","volume":"70","author":"Steinschneider A","year":"1982","journal-title":"Pediatrics."},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(84)80335-2"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(84)80502-8"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.61.3.227"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1969.sp008744"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1962.sp006950"},{"key":"e_1_2_1_24_2","first-page":"353","article-title":"The cardiovascular response to laryngeal water administration in young lambs","volume":"4","author":"Grogaard J","year":"1982","journal-title":"J Dev Physiol."},{"key":"e_1_2_1_25_2","first-page":"635","article-title":"Clinically unsuspected unsuspected hypoxia during sleep and feeding in infants with bronchopulmonary dysplasia","volume":"81","author":"Garg M","year":"1988","journal-title":"Pediatrics."}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.1950050408","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.1950050408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T03:22:01Z","timestamp":1697944921000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.1950050408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,1]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1988,1]]}},"alternative-id":["10.1002\/ppul.1950050408"],"URL":"https:\/\/doi.org\/10.1002\/ppul.1950050408","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,1]]}}}