{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:01:36Z","timestamp":1773280896066,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2005,10,21]],"date-time":"2005-10-21T00:00:00Z","timestamp":1129852800000},"content-version":"vor","delay-in-days":4556,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[1993,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>High\u2010frequency jet ventilation (HFJV) was used in 29 children with severe ARDS complicated by pulmonary barotrauma (PST). Treatment with HFJV was begun when PBT was progressing over a 24\u2010h period while receiving conventional ventilation (CV). The mean (\u00b1SD) age was 0.95 \u00b1 1.21 years (range, 0.03\u20104 years). The most common diagnosis was viral pneumonia <jats:italic>(n<\/jats:italic> = 17); other diagnoses included aspiration pneumonitis (n = 4), bacterial pneumonia <jats:italic>(n<\/jats:italic> = 3), multiple trauma <jats:italic>(n<\/jats:italic> = 2), and near\u2010drowning <jats:italic>(n<\/jats:italic> = 3). The Bunnell Life\u2010Pulse ventilator was used at a rate of 240\/min or 300\/min, with inspiratory time of 0.02 sec. Twenty children survived (69%). Survivors and nonsurvivors had equal disease severity prior to HFJV as assessed by ventilator settings, alveolar\u2010to\u2010arterial oxygen tension gradient, oxygenation index, and blood gas values. Survivors had spent significantly less time on conventional ventilation prior to HFJV than nonsurvivors, with a mean (\u00b1SD) of 3.7 \u00b1 2.1 days vs 9.6 5 4.5 days, respectively <jats:italic>(P<\/jats:italic> &lt; 0.05). Survivors underwent an average of 4.4 \u00b1 3.9 days of HFJV, which supported adequate gas exchange with lower airway pressures, and produced resolution or significant improvement in airleak on chest radiograph. In conclusion, we speculate that the application of HFJV early in the course of severe hypoxemic respiratory failure complicated by airleak, allows the reduction of airway pressures, thereby minimizing pulmonary barotrauma and allowing the lung to recover from the underlying insult. Further controlled evaluation of HFJV in this high risk group of patients is warranted. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ppul.1950150504","type":"journal-article","created":{"date-parts":[[2007,3,6]],"date-time":"2007-03-06T18:29:09Z","timestamp":1173205749000},"page":"279-286","source":"Crossref","is-referenced-by-count":31,"title":["High\u2010frequency jet ventilation in children with the adult respiratory distress syndrome complicated by pulmonary barotrauma"],"prefix":"10.1002","volume":"15","author":[{"given":"David W.","family":"Smith","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorry R.","family":"Frankel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melinda T.","family":"Derish","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert R.","family":"Moody","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"III","given":"Lehman E.","family":"Black","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley E.","family":"Chipps","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence H.","family":"Mathers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,21]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198007000-00002"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1542\/peds.67.6.790","article-title":"Adult respiratory distress syndrome in a pediatric intensive care unit: Predisposing conditions, clinical course, and outcome","volume":"67","author":"Lyrene RK","year":"1981","journal-title":"Pediatrics"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1969.01340150047007"},{"key":"e_1_2_1_5_2","first-page":"73","article-title":"Acute respiratory failure in the surgical patient","volume":"41","author":"Barash PG","year":"1977","journal-title":"Conn Med."},{"key":"e_1_2_1_6_2","first-page":"407","article-title":"Intensive care unit radiology problems of interpretation","volume":"3","author":"Ovenfors C","year":"1978","journal-title":"Radiol Clin North Am."},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-197307000-00001"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1148\/121.1.25"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","unstructured":"MariniJJ KelsenSG.Re\u2010targeting ventilatory objectives in adult respiratory distress syndrome. 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