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A CF gene study on the other sibling years later, however, led to further investigation and eventually to a change of diagnosis. As interesting and important as gene analysis is in CF, one must always look at each patient in the big picture. Included in the picture, in addition to the state\u2010of\u2010the\u2010art genotype, is the phenotype, or (to simplify) the back\u2010to\u2010basic clinical manifestations. Pediatr Pulmonol. 2005; 39:379\u2013381. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ppul.20172","type":"journal-article","created":{"date-parts":[[2005,1,27]],"date-time":"2005-01-27T18:46:49Z","timestamp":1106851609000},"page":"379-381","source":"Crossref","is-referenced-by-count":0,"title":["Misdiagnosing cystic fibrosis in the era of gene analysis: Case reports"],"prefix":"10.1002","volume":"39","author":[{"given":"Chuanpit","family":"Moser","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliezer","family":"Nussbaum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohan","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,2,24]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.10437"},{"key":"e_1_2_1_3_2","first-page":"5","volume-title":"Cystic fibrosis medical care","author":"Orenstein DM","year":"2000"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/humu.9183"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-002-0737-z"},{"key":"e_1_2_1_6_2","first-page":"57","article-title":"Newborn screening for CF: the practical implications","volume":"97","author":"Southern KW","year":"2004","journal-title":"J R Soc Med [Suppl]"},{"key":"e_1_2_1_7_2","first-page":"387","article-title":"Gastrointestinal manifestations of cystic fibrosis","volume":"6","author":"Flick JA","year":"1995","journal-title":"Adolesc Med"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.3928\/0090-4481-19970401-06"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.924"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1586\/14737159.4.4.465"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0929-693X(03)90046-7"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2350-5-8"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0929-693X(03)90056-X"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004390100490"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0041-87812003000500005"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.152.5.7582320"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2350-5-19"},{"key":"e_1_2_1_18_2","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.5858\/2003-127-1133-CCICFS","article-title":"Current challenges in cystic fibrosis screening","volume":"127","author":"Lyon E","year":"2003","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/00063198-200311000-00009"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-2712(03)00033-7"},{"key":"e_1_2_1_21_2","first-page":"17","article-title":"The emergence of Stenotrophomonas maltophilia as a significant nosocomial pathogen at the University Hospital of the West Indies","volume":"53","author":"Nicholson AM","year":"2004","journal-title":"West Indian Med J"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.20172","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.20172","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T18:58:58Z","timestamp":1700161138000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.20172"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2,24]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,4]]}},"alternative-id":["10.1002\/ppul.20172"],"URL":"https:\/\/doi.org\/10.1002\/ppul.20172","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,2,24]]}}}