{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:47:30Z","timestamp":1790722050237,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,11,10]],"date-time":"2005-11-10T00:00:00Z","timestamp":1131580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2006,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of our study was to evaluate the efficacy of adenotonsillectomy for the treatment of obstructive sleep apnea syndrome (OSA) in pediatric patients with Prader\u2010Willi syndrome (PWS), and to describe the postoperative complications. Five patients (4 males; median age, 4.4 years; range, 1.6\u201314.2 years) were studied. All patients underwent an overnight cardiorespiratory sleep study. All patients had adenotonsillar hypertrophy (ATH), and two were also obese. The preoperative obstructive apnea\/hypopnea index (AHI; median and range) was 12.2 (9.0\u201319.9) events\/hr; the mean oxygen saturation was 95 (79\u201396)%; the nadir oxygen saturation was 71 (58\u201378)%; and the oxygen desaturation index (ODI) was 15.8 (11.4\u201335.9) events\/hr. Preoperatively, patients were classified as having moderate to severe OSA. A second sleep study, performed 16 (3\u201343) months after adenotonsillectomy, showed a significant decrease in AHI (<jats:italic>P<\/jats:italic>\u2009=\u20090.009) and ODI (<jats:italic>P<\/jats:italic>\u2009=\u20090.009). Mean and nadir oxygen saturation did not differ significantly postsurgery (<jats:italic>P<\/jats:italic>\u2009=\u20090.188, <jats:italic>P<\/jats:italic>\u2009=\u20090.073, respectively). Four out of five children showed at least one postoperative complication. Difficult awakening from anesthesia, hemorrhages, and respiratory complications requiring reintubation and\/or supplemental oxygen administration were observed. In conclusion, patients with PWS and OSA who underwent adenotonsillectomy showed a significant decrease in AHI and number of oxygen desaturations. Pediatr Pulmonol. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ppul.20334","type":"journal-article","created":{"date-parts":[[2005,11,16]],"date-time":"2005-11-16T21:51:51Z","timestamp":1132177911000},"page":"74-79","source":"Crossref","is-referenced-by-count":43,"title":["Adenotonsillectomy for Obstructive Sleep Apnea in Children with Prader\u2010Willi Syndrome"],"prefix":"10.1002","volume":"41","author":[{"given":"M.","family":"Pavone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.G.","family":"Paglietti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Petrone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Crin\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.C.","family":"De Vincentiis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato","family":"Cutrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,11,10]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"27","volume-title":"The Prader\u2010Willi syndrome","author":"Holm VA","year":"1981"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320350306"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.91.2.398"},{"key":"e_1_2_1_5_2","first-page":"45","volume-title":"The Prader\u2010Willi syndrome","author":"Hanson J","year":"1981"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.10152"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.164.1.2008171"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.153.2.8564147"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.109.4.704"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(03)00125-3"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1990.01870060043006"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.93.5.784"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1997.01900050067009"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.320.7244.1240"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.102.4.1145"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.109.3.680"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/146.5_Pt_1.1235"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.125.3.872"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.02.024"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.87.5.438"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004310050555"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1159\/000082745"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2004.08.002"},{"key":"e_1_2_1_24_2","first-page":"1297","article-title":"Growth hormone therapy for Prader\u2010Willi syndrome: a critical appraisal","volume":"17","author":"Allen DB","year":"2004","journal-title":"J Pediatr Endocrinol Metab [Suppl]"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1994.tb01213.x"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.10.007"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.20334","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.20334","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T19:55:00Z","timestamp":1696622100000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.20334"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11,10]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["10.1002\/ppul.20334"],"URL":"https:\/\/doi.org\/10.1002\/ppul.20334","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,11,10]]}}}